Cerebrospinal fluid lactate and lactate dehydrogenase activity in the rapid diagnosis of bacterial meningitis
dc.contributor.author | Donald, P. R. | en_ZA |
dc.contributor.author | Malan, C. | en_ZA |
dc.date.accessioned | 2011-03-18T14:57:32Z | |
dc.date.available | 2011-03-18T14:57:32Z | |
dc.date.issued | 1986 | |
dc.description | CITATION: Donald, P. R. & Malan, C. 1986. Cerebrospinal fluid lactate and lactate dehydrogenase activity in the rapid diagnosis of bacterial meningitis. South African Medical Journal, 69:39-42. | |
dc.description | The original publication is available at http://www.samj.org.za | |
dc.description.abstract | The value of cerebrospinal fluid (CSF) lactate and lactate dehydrogenase (LD) activity in the rapid diagnosis of meningitis was investigated in three groups of patients - a 'no meningitis', an aseptic meningitis and a bacterial meningitis group. The sensitivity achieved in the detection of bacterial meningitis by CSF lactate values of 2,85 mmol/l (93,8%) and 3,9 mmol/l (89,6%) was greater than that reached by conventional chemical investigations using a CSF protein value of 1 g/l (81,5%) or a CSF glucose value of 2,2 mmol/l (68,8%) as the indicator. The sensitivity of an absolute CSF LD value of 40 U/l (86,3%) in the detection of bacterial meningitis was slightly lower than that of a CSF protein value of 1 g/l (87%) and better than the sensitivity of either a CSF/serum LD ratio of 0,1:1,0 (83,9%) or a CSF glucose level of 2,2 mmol/l (76,3%). As with conventional CSF chemistry, both investigations may give normal values in the presence of bacterial meningitis. | |
dc.description.version | Publisher’s version | |
dc.format.extent | 4 pages | |
dc.identifier.issn | 2078-5135 (online) | |
dc.identifier.issn | 0256-9574 (print) | |
dc.identifier.uri | http://hdl.handle.net/10019.1/7478 | |
dc.language.iso | en | |
dc.publisher | Health & Medical Publishing Group | |
dc.rights.holder | South African Medical Journal | |
dc.subject | Meningitis | en_ZA |
dc.subject | Cerebrospinal fluid | en_ZA |
dc.title | Cerebrospinal fluid lactate and lactate dehydrogenase activity in the rapid diagnosis of bacterial meningitis | en_ZA |
dc.type | Article |
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