The role of prenatal alcohol exposure in abruptio placentae
| dc.contributor.author | Du Toit, M. M. | |
| dc.contributor.author | Smith, M. | |
| dc.contributor.author | Odendaal, H. J. | |
| dc.date.accessioned | 2013-09-03T08:06:48Z | |
| dc.date.available | 2013-09-03T08:06:48Z | |
| dc.date.issued | 2010-12 | |
| dc.description | The original publication is available at http://www.samj.org.za | en_ZA |
| dc.description.abstract | Objective. To investigate the association between preconception and prenatal alcohol use and abruptio placentae. Methods. A case-control study of women with the clinical diagnosis of abruptio placentae, 65 cases and 66 controls, at Tygerberg Academic Hospital, Western Cape, South Africa. Women in whom a retroplacental blood clot, covering at least 15% of the placental surface, was found at delivery at 24 weeks’ gestation or later were asked to complete a timeline follow-back questionnaire to determine their alcohol intake 12 and 3 months before and during pregnancy. The same questionnaire was administered to a control group of high-risk women who had no antepartum haemorrhage. Outcome. Women who drank alcohol 12 months before conception were more than 4 times more likely to develop abruptio placentae than the control group (odds ratio (OR) 4.49, p=0.00009). Women who drank alcohol 3 months prior to conception were 3 times more likely to develop abruptio placentae than the control group (OR 3.06, p=0.003). Drinking alcoholic beverages during pregnancy carried a more than 3 times greater risk of developing abruptio placentae (OR 3.52, p=0.0006). In the study group, women consumed a mean of 13.6, 12.0 and 11.2 standard drinks in a typical week at 12 and 3 months before and during pregnancy, respectively. The study group demonstrated a binge-drinking pattern, with two to four sessions per month. Conclusion. An association was found between preconception and prenatal consumption of alcohol and abruptio placentae. | en_ZA |
| dc.description.version | Publishers' Version | en_ZA |
| dc.format.extent | 4 p. | |
| dc.identifier.citation | Du Toit, M. M., Smith, M. & Odendaal, H. J. 2010. The role of prenatal alcohol exposure in abruptio placentae. South African Medical Journal, 100(12):832-835. | en_ZA |
| dc.identifier.issn | 2078-5135 (online) | |
| dc.identifier.issn | 0256-9574 (print) | |
| dc.identifier.uri | http://hdl.handle.net/10019.1/85395 | |
| dc.language.iso | en_ZA | en_ZA |
| dc.publisher | Health and Medical Publishing Group (HMPG) | en_ZA |
| dc.rights.holder | Authors retain copyright | en_ZA |
| dc.subject | Alcoholism in pregnancy | en_ZA |
| dc.subject | Abruptio placentae | en_ZA |
| dc.title | The role of prenatal alcohol exposure in abruptio placentae | en_ZA |
| dc.type | Article | en_ZA |