A retrospective analysis of mitral valve pathology in the setting of bicuspid aortic valves

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dc.contributor.authorVan Rensburg, Annarien_ZA
dc.contributor.authorHerbst, Philipen_ZA
dc.contributor.authorDoubell, Antonen_ZA
dc.date.accessioned2018-08-17T09:40:41Z
dc.date.available2018-08-17T09:40:41Z
dc.date.issued2017
dc.descriptionCITATION: Van Rensburg, A., Herbst, P. & Doubell, A. 2017. A retrospective analysis of mitral valve pathology in the setting of bicuspid aortic valves. Echo Research and Practice, 4(2):21-28, doi:10.1530/ERP-17-0016.
dc.descriptionThe original publication is available at http://www.echorespract.com
dc.description.abstractThe therapeutic implications of bicuspid aortic valve associations have come under scrutiny in the transcatheter aortic valve implantation era. We evaluate the spectrum of mitral valve disease in patients with bicuspid aortic valves to determine the need for closer echocardiographic scrutiny/follow-up of the mitral valve. A retrospective analysis of echocardiograms done at a referral hospital over five years was conducted in patients with bicuspid aortic valves with special attention to congenital abnormalities of the mitral valve. One hundred and forty patients with a bicuspid aortic valve were included. A congenital mitral valve abnormality was present in eight (5.7%, P = 0.01) with a parachute mitral valve in four (2.8%), an accessory mitral valve leaflet in one (0.7%), mitral valve prolapse in one, a cleft in one and the novel finding of a trileaflet mitral valve in one. Minor abnormalities included an elongated anterior mitral valve leaflet (P < 0.001), the increased incidence of physiological mitral regurgitation (P < 0.001), abnormal papillary muscles (P = 0.002) and an additional chord or tendon in the left ventricle cavity (P = 0.007). Mitral valve abnormalities occur more commonly in patients with bicuspid aortic valves than matched healthy individuals. The study confirms that abnormalities in these patients extend beyond the aorta. These abnormalities did not have a significant functional effect.en_ZA
dc.description.urihttp://www.echorespract.com/content/4/2/21
dc.description.versionPublisher's version
dc.format.extent8 pages
dc.identifier.citationVan Rensburg, A., Herbst, P. & Doubell, A. 2017. A retrospective analysis of mitral valve pathology in the setting of bicuspid aortic valves. Echo Research and Practice, 4(2):21-28, doi:10.1530/ERP-17-0016
dc.identifier.issn2055-0464 (online)
dc.identifier.otherdoi:10.1530/ERP-17-0016
dc.identifier.urihttp://hdl.handle.net/10019.1/104279
dc.language.isoen_ZAen_ZA
dc.publisherBioScientifica
dc.rights.holderAuthors retain copyright
dc.subjectMitral valveen_ZA
dc.subjectCongenital heart diseaseen_ZA
dc.subjectEchocardiographyen_ZA
dc.titleA retrospective analysis of mitral valve pathology in the setting of bicuspid aortic valvesen_ZA
dc.typeArticleen_ZA
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