Polycystic ovarian syndrome (PCOS) : an audit of how many PCOS patients struggle to lose weight with recommended diet management in a Tygerberg Hospital population

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Stellenbosch : Stellenbosch University
ENGLISH SUMMARY: Introduction: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder of women in the reproductive eage (Matsaseng, 2017). It has a variable clinical appearance, with manifestations that include menstrual irregularities, hirsutism, acne, obesity, infertility, impaired glucose tolerance, diabetes, and a significant cardiovascular risk profile (Teedeetal., 2010). Globally, the prevalence of PCOS is 5% to 10% of women in the reproductive age. Insub-Saharan Africa, studies on the prevalence of PCOS are scarce and values range from 16% to 32% (Pembe & Abeid, 2009). Materials and Methods: Aim of the study: To evaluate how many PCOS patients struggle to lose weight with recommended diet management in a Tygerberg Hospital population. Study design: This is a retrospective observational study. Setting: The setting of the study is the Reproductive Medicine Unit of the Department of Obstetrics and Gynaecology at the Tygerberg Academic Hospital. Results: A total of 73 women were recruited for the study between June and December 2021. The average age of the study participants was 29.3years. All of the study participants (100 %) struggled to lose there commended weight. Average BMI was 38.1kg/m2 and 37.7kg/m2 at first and last visit, respectively. We created two BMI category variables, each with four levels, namely pre-obese, obese class 1, obese class 2, and obese class 3. Most of the participants were obese class 2 at both the first and last visits. The classification was pre-obese (25 to 29.9), class 1 (30 to 34.9), which is associated with a mildly increased risk of co-morbidities, class 2 (35 to 39.9), which is associated with a moderately increased risk of co-morbidities, and class 3 (≥40), which is associated with a severe risk of co-morbidities. Conclusion: Inconclusion, our study shows that 38 % of patients with PCOS at Tygerberg Academic Hospital are obese, and none of the patients succeeded in losing the recommended weight following the initial standard therapy offered.
AFRIKAANSE OPSOMMING: Geen opsomming beskikbaar.
Thesis (MMed)--Stellenbosch University, 2022.