Chest radiographs of neonates with respiratory failure caused by congenital syphilis

Simple item page
dc.contributor.authorPieper C.H.
dc.contributor.authorVan Gelderen W.F.C.
dc.contributor.authorSmith J.
dc.contributor.authorKirsten G.F.
dc.contributor.authorMohrcken S.
dc.contributor.authorGie R.P.
dc.date.accessioned2011-05-15T16:17:43Z
dc.date.available2011-05-15T16:17:43Z
dc.date.issued1995
dc.description.abstractCongenital syphilis still occurs in newborn babies and the prevalence has increased in recent years, especially in developing countries. This has led to an increase in the number of babies with congenital syphilis requiring intensive care for respiratory failure. The early recognition of this disease could lead to the institution of timely and appropriate treatment. In this study the radiological picture of syphilitic pneumonitis is described in 20 neonates admitted to our neonatal intensive care unit requiring ventilation for respiratory failure. The radiological picture of the babies with syphilis was compared to 20 babies with other causes of respiratory distress. The radiological picture in 17 babies demonstrated a coarse nodular pattern in addition to band-like opacities radiating from the hilar regions. The nodular opacities became confluent on follow-up radiographs. In 13 cases, the proximal humeri showed changes typical of congenital syphilis. Two of the three babies with syphilis who did not have the typical chest radiological picture had bony involvement visible on the chest radiograph. Both the sensitivity and specificity of radiographic diagnosis were 75% with a positive and negative predictive value of 75%. The diagnosis of congenital syphilitic pneumonitis can therefore be suspected on chest radiographs and should be included in the differential diagnosis of any baby who presents with an interstitial pattern on chest radiography.
dc.description.versionArticle
dc.identifier.citationPediatric Radiology
dc.identifier.citation25
dc.identifier.citation3
dc.identifier.issn03010449
dc.identifier.other10.1007/BF02021534
dc.identifier.urihttp://hdl.handle.net/10019.1/14339
dc.subjectarticle
dc.subjectclinical article
dc.subjectcongenital syphilis
dc.subjectdeveloping country
dc.subjectdifferential diagnosis
dc.subjectfollow up
dc.subjecthuman
dc.subjectlung
dc.subjectnewborn
dc.subjectnewborn intensive care
dc.subjectpneumonia
dc.subjectprevalence
dc.subjectpriority journal
dc.subjectrespiratory failure
dc.subjectthorax radiography
dc.subjectCase-Control Studies
dc.subjectDiagnosis, Differential
dc.subjectHuman
dc.subjectHyaline Membrane Disease
dc.subjectInfant, Newborn
dc.subjectLung
dc.subjectObserver Variation
dc.subjectPredictive Value of Tests
dc.subjectPrevalence
dc.subjectRespiration, Artificial
dc.subjectRespiratory Insufficiency
dc.subjectSensitivity and Specificity
dc.subjectSyphilis, Congenital
dc.titleChest radiographs of neonates with respiratory failure caused by congenital syphilis
dc.typeArticle
Files
Collections
Stellenbosch University - Scopus Tygerberg Hospital Publications