Prevalence of and risk factors for retinopathy of prematurity in a cohort of preterm infants treated exclusively with non-invasive ventilation in the first week after birth

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dc.contributor.authorVan der Merwe, S. K.en_ZA
dc.contributor.authorFreeman, N.en_ZA
dc.contributor.authorBekker, A.en_ZA
dc.contributor.authorHarvey, J.en_ZA
dc.contributor.authorSmith, J.en_ZA
dc.date.accessioned2014-07-07T12:33:34Z
dc.date.available2014-07-07T12:33:34Z
dc.date.issued2013-01-14
dc.descriptionCITATION: Van der Merwe, S. K. et al. 2013. Prevalence of and risk factors for retinopathy of prematurity in a cohort of preterm infants treated exclusively with non-invasive ventilation in the first week after birth. South African Medical Journal, 103(2):96-101, doi:10.7196/SAMJ.6131.
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractObjectives. To determine the current prevalence of retinopathy of prematurity (ROP) in premature babies treated with non-invasive ventilation at Tygerberg Children’s Hospital, Parow, Cape Town, South Africa, and to identify risk factors associated with the development of ROP. Methods. A retrospective medical records review of infants screened for ROP during a 2-year period (January 2009 - December 2010). Infants who did not receive invasive ventilation during the first week of life were included. Twenty-four previously reported risk factors for the development of ROP were identified for use in a multivariate logistic regression (MLR) analysis. Results. A total of 356 patients were included. The overall prevalence of ROP was 21.8% and that of clinically significant ROP (CSROP) 4.4%. The risk factors with a statistically significant association with the development of ROP on MLR analysis were severe apnoea (p=0.0005) and decreasing birth weight (p=0.0382). Conclusions. There is a low prevalence of ROP in the cohort of preterm infants treated exclusively with non-invasive ventilation in the first week of life. The risk factors of importance in our population were severe apnoea and lower birth weight. Birth weight is a practical and reproducible variable that can be used to aid development of ROP screening criteria.
dc.description.urihttp://www.samj.org.za/index.php/samj/article/view/6131
dc.description.versionPublisher's version
dc.format.extent5 pages
dc.identifier.citationVan der Merwe, S. K. et al. 2013. Prevalence of and risk factors for retinopathy of prematurity in a cohort of preterm infants treated exclusively with non-invasive ventilation in the first week after birth. South African Medical Journal, 103(2):96-101, doi:10.7196/SAMJ.6131.
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.otherdoi:10.7196/SAMJ.6131
dc.identifier.urihttp://hdl.handle.net/10019.1/94853
dc.language.isoen_ZA
dc.publisherHealth & Medical Publishing Group
dc.rights.holderAuthors retain copyright
dc.subjectRetinopathy of prematurityen_ZA
dc.subjectPrematurity complications -- Medical careen_ZA
dc.subjectRetrolental fibroplasiaen_ZA
dc.subjectRespirators (Medical equipment)en_ZA
dc.subjectNon-invasive ventilationen_ZA
dc.titlePrevalence of and risk factors for retinopathy of prematurity in a cohort of preterm infants treated exclusively with non-invasive ventilation in the first week after birthen_ZA
dc.typeArticle
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