Appropriate indications for positron emission tomography/computed tomography : College of Nuclear Physicians of the Colleges of Medicine of South Africa

dc.contributor.authorSathekge, Mikeen_ZA
dc.contributor.authorWarwick, James M.en_ZA
dc.contributor.authorDoruyter, Alexen_ZA
dc.contributor.authorVorster, Marizaen_ZA
dc.date.accessioned2017-10-17T08:47:23Z
dc.date.available2017-10-17T08:47:23Z
dc.date.issued2016
dc.descriptionCITATION: Sathekge, M., et al. 2016. Appropriate indications for positron emission tomography/computed tomography : College of Nuclear Physicians of the Colleges of Medicine of South Africa. South African Medical Journal, 105(11):894-896, doi:10.7196/SAMJ.2015.v105i11.10180.en_ZA
dc.descriptionThe original publication is available at http://www.samj.org.zaen_ZA
dc.description.abstractIndividualised patient treatment approaches demand precise determination of initial disease extent combined with early, accurate assessment of response to treatment, which is made possible by positron emission tomography/computed tomography (PET/CT). PET is a non-invasive tool that provides tomographic images and quantitative parameters of perfusion, cell viability, and proliferation and/or metabolic activity of tissues. Fusion of the functional information with the morphological detail provided by CT as PET/CT can provide clinicians with a sensitive and accurate one-step whole-body diagnostic and prognostic tool, which directs and changes patient management. Three large-scale national studies published by the National Oncologic PET Registry in the USA have shown that imaging with PET changes the intended patient management strategy in 36.5% to 49% of cases, with consistent results across all cancer types. The proven clinical effectiveness and growing importance of PET/CT have prompted the College of Nuclear Physicians of South Africa, in collaboration with university hospitals, to develop a list of recommendations on the appropriate use of fluorine-18-fluorodeoxyglucose (18F-FDG) and non-18F-FDG PET/CT in oncology, cardiology, neurology and infection/inflammation. It is expected that other clinical situations will be added to these recommendations, provided that they are based upon solid clinical evidence. These recommendations are intended to offer advice regarding contemporary applications of PET/CT, as well as indicating novel developments and potential future indications. The CNP believes that these recommendations will serve an important and relevant role in advising referring physicians on the appropriate use of 18F-FDG and non-18F-FDG PET/CT. More promising clinical applications will be possible in the future, as newer PET tracers become more readily available.en_ZA
dc.description.urihttp://www.samj.org.za/index.php/samj/article/view/10180
dc.description.versionPublisher's versionen_ZA
dc.format.extent3 pagesen_ZA
dc.identifier.citationSathekge, M., et al. 2016. Appropriate indications for positron emission tomography/computed tomography : College of Nuclear Physicians of the Colleges of Medicine of South Africa. South African Medical Journal, 105(11):894-896, doi:10.7196/SAMJ.2015.v105i11.10180en_ZA
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.otherdoi:10.7196/SAMJ.2015.v105i11.10180
dc.identifier.urihttp://hdl.handle.net/10019.1/102345
dc.language.isoen_ZAen_ZA
dc.publisherHealth & Medical Publishing Groupen_ZA
dc.rights.holderSouth African Medical Journalen_ZA
dc.subjectNuclear physiciansen_ZA
dc.subjectTomographyen_ZA
dc.subjectTomography, Emissionen_ZA
dc.subjectCancer -- Tomography -- South Africaen_ZA
dc.titleAppropriate indications for positron emission tomography/computed tomography : College of Nuclear Physicians of the Colleges of Medicine of South Africaen_ZA
dc.typeArticleen_ZA
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