Surrogate pregnancies in patients with Mayer-Rokitansky-Kustner-Hauser syndrome and severe teratozoospermia

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dc.contributor.authorVan Waart J.
dc.contributor.authorKruger T.F.
dc.date.accessioned2011-05-15T16:15:34Z
dc.date.available2011-05-15T16:15:34Z
dc.date.issued2000
dc.description.abstractThe challenge of the case presented was threefold: congenital absent uterus (Mayer-Rokitansky-Kustner-Hauser syndrome), a request for surrogacy, and teratozoospermia in the husband (6% normal morphology according to the Tygerberg strict criteria). Surrogacy was dealt with by means of guidelines proposed by the SA Law Commission after a surrogate mother was found. The gestational carrier was synchronized with the genetic donor with congenital absent uterus, the main aim being assisted reproduction. Two gamete intrafallopian transfer (GIFT) procedures were performed, both unsuccessful. Poor fertilization of excess GIFT oocytes was also observed. Three intracytoplasmic sperm injection procedures were then performed. The first two were unsuccessful and the third ensued in a singleton pregnancy. Hormonal support (progesterone and estradriol valerate until 12 weeks pregnancy duration) was given. The pregnancy resulted in the normal delivery of a healthy male infant at full term. Psychological support was given to mother and surrogate throughout pregnancy, as well as thereafter. The success of this case gives hope to infertile couples with severe infertility factors.
dc.description.versionArticle
dc.identifier.citationArchives of Andrology
dc.identifier.citation45
dc.identifier.citation2
dc.identifier.issn01485016
dc.identifier.urihttp://hdl.handle.net/10019.1/13391
dc.subjectestradiol valerate
dc.subjectprogesterone
dc.subjectadult
dc.subjectarticle
dc.subjectcase report
dc.subjectfemale
dc.subjectfertilization in vitro
dc.subjectgamete intrafallopian transfer
dc.subjecthuman
dc.subjectintracytoplasmic sperm injection
dc.subjectlaw
dc.subjectmale
dc.subjectmale infertility
dc.subjectmother
dc.subjectoocyte donation
dc.subjectpractice guideline
dc.subjectpregnancy
dc.subjectpriority journal
dc.subjectpsychotherapy
dc.subjectRokitansky syndrome
dc.subjectSouth Africa
dc.subjectspermatozoon abnormality
dc.subjecttreatment outcome
dc.subjectAdult
dc.subjectEstradiol
dc.subjectFemale
dc.subjectGamete Intrafallopian Transfer
dc.subjectHumans
dc.subjectInfertility, Female
dc.subjectInfertility, Male
dc.subjectMale
dc.subjectPregnancy
dc.subjectProgesterone
dc.subjectSperm Injections, Intracytoplasmic
dc.subjectSpermatozoa
dc.subjectSurrogate Mothers
dc.subjectSyndrome
dc.subjectUterus
dc.titleSurrogate pregnancies in patients with Mayer-Rokitansky-Kustner-Hauser syndrome and severe teratozoospermia
dc.typeArticle
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