Relationship between Human Sperm Morphology and Acrosomal Function

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dc.contributor.authorMenkveld R.
dc.contributor.authorEl-Garem Y.
dc.contributor.authorSchill W.-B.
dc.contributor.authorHenkel R.
dc.date.accessioned2011-05-15T16:16:50Z
dc.date.available2011-05-15T16:16:50Z
dc.date.issued2003
dc.description.abstractPurpose: In this study, we investigated the relationship between functionality of the acrosome and sperm morphology. Methods: Acrosome reaction (AR) was separately determined in live and dead sperm and in those with normal, small, and large sized acrosomes by means of the triple stain. Morphology was analyzed according to strict criteria after Papanicolaou stain. Results: AR and morphology correlated regarding detection of large and small sized acrosomes, but not for normal sized acrosomes. Spontaneous AR was significantly influenced by acrosomal size. Sperm with large (11.4%) and normal (9.2%) acrosomes exhibited a significantly higher percentage of life spontaneously acrosome-reacted sperm than those with small acrosomes (4.5%). Sperm with small acrosomes were associated with a higher percentage of cell death. Conclusion: The results indicate that sperm with small acrosomes are more susceptible to cell death and nonphysiological acrosomal loss. Acrosome size reflects the physiological capability of sperm function and therefore male fertility potential.
dc.description.versionArticle
dc.identifier.citationJournal of Assisted Reproduction and Genetics
dc.identifier.citation20
dc.identifier.citation10
dc.identifier.issn10580468
dc.identifier.other10.1023/A:1026288710638
dc.identifier.urihttp://hdl.handle.net/10019.1/13956
dc.subjectacrosome
dc.subjectacrosome reaction
dc.subjectarticle
dc.subjectcell death
dc.subjectcontrolled study
dc.subjecthuman
dc.subjectmale
dc.subjectmale fertility
dc.subjectmorphology
dc.subjectPapanicolaou test
dc.subjectpriority journal
dc.subjectsemen analysis
dc.subjectAcrosome
dc.subjectAcrosome Reaction
dc.subjectColoring Agents
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectROC Curve
dc.subjectSpermatozoa
dc.titleRelationship between Human Sperm Morphology and Acrosomal Function
dc.typeArticle
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