Clinical and neuropsychological predictors of posttraumatic stress disorder

dc.contributor.authorSuliman, Sharain
dc.contributor.authorStein, Dan J.
dc.contributor.authorSeedat, Soraya
dc.contributor.otherPsychiatryen_ZA
dc.date.accessioned2015-07-23T13:34:11Z
dc.date.available2015-07-23T13:34:11Z
dc.date.issued2014-11
dc.descriptionPublication of this article was funded by the Stellenbosch University Open Access Fund
dc.descriptionThe original publication is available at http://www.md-journal.com
dc.descriptionPlease cite as follows:
dc.descriptionSuliman, S., Stein, D. J., & Seedat, S. 2014. Clinical and neuropsychological predictors of posttraumatic stress disorder. Medicine, 93(22), doi:10.1097/MD.0000000000000113.
dc.description.abstractAbstract: Although acute responses to traumatic stress generally resolve within a few weeks, some individuals experience severe and persistent problems, such as posttraumatic stress disorder (PTSD). While studies have identified a variety of predictors of PTSD, not all data are consistent. This longitudinal study examined the predictive power of neurocognitive deficits with regard to PTSD severity. One hundred thirty one road traffic collision (RTC) survivors were included within 2 weeks of the RTC and followed up 3 and 6 months later to determine severity of PTSD. Impairment on tests of information processing, executive functioning, verbal learning, and motor speed predicted PTSD severity when neuropsychological, clinical, and sociodemographic factors were all taken into account. Clinical variables (initial symptoms, psychiatric diagnoses, disability, trait anxiety, perceived stress, negative cognitions, and sleep) were associated with 3 and 6-month PTSD severity, but only trait anxiety was predictive of PTSD severity. Ethnicity and education were also found to be predictive. These findings suggest implementation of a holistic approach to screening for PTSD and support a need for interventions that target neurocognitive, clinical, and social variables. Early targeted profiling of this group of trauma survivors can inform early clinical interventions and policy.
dc.description.urihttp://www.md-journal.comen_ZA
dc.description.versionAlthough acute responses to traumatic stress generally resolve within a few weeks, some individuals experience severe and persistent problems, such as posttraumatic stress disorder (PTSD). While studies have identified a variety of predictors of PTSD, not all data are consistent. This longitudinal study examined the predictive power of neurocognitive deficits with regard to PTSD severity. One hundred thirty one road traffic collision (RTC) survivors were included within 2 weeks of the RTC and followed up 3 and 6 months later to determine severity of PTSD. Impairment on tests of information processing, executive functioning, verbal learning, and motor speed predicted PTSD severity when neuropsychological, clinical, and sociodemographic factors were all taken into account. Clinical variables (initial symptoms, psychiatric diagnoses, disability, trait anxiety, perceived stress, negative cognitions, and sleep) were associated with 3 and 6-month PTSD severity, but only trait anxiety was predictive of PTSD severity. Ethnicity and education were also found to be predictive. These findings suggest implementation of a holistic approach to screening for PTSD and support a need for interventions that target neurocognitive, clinical, and social variables. Early targeted profiling of this group of trauma survivors can inform early clinical interventions and policy.en_ZA
dc.description.versionPublishers' version
dc.identifier.citationSuliman, S., Stein, D. J., & Seedat, S. 2014. Clinical and neuropsychological predictors of posttraumatic stress disorder. Medicine, 93(22), doi:10.1097/MD.0000000000000113.en_ZA
dc.identifier.issn1536-5964 (Online)
dc.identifier.issn0025-7974 (Print)
dc.identifier.otherdoi:10.1097/MD.0000000000000113
dc.identifier.urihttp://hdl.handle.net/10019.1/97248
dc.publisherLippincott, Williams & Wilkinsen_ZA
dc.rights.holderAuthor holds the copyright
dc.subjectNeuropsychological predictorsen_ZA
dc.subjectPosttraumatic stress disorderen_ZA
dc.subjectTraumatic stressen_ZA
dc.titleClinical and neuropsychological predictors of posttraumatic stress disorderen_ZA
dc.typeArticleen_ZA
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