Cavitation of the Ghon focus in an HIV-infected infant who acquired tuberculosis after the initiation of HAART

Date
2009
Authors
Innes S.
Schaaf H.S.
Cotton M.F.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Tuberculosis immune reconstitution inflammatory syndrome (IRIS) may present as new or worsening cavitation. We present an HIV-infected infant in whom TB infection and subsequent cavitation of the Ghon focus appeared to coincide with immune reconstitution due to highly active antiretroviral therapy (HAART). TB-IRIS in response to infection that occurs after starting HAART has not previously been described.
Description
Keywords
CD4 antigen, isoniazid, lamivudine, lopinavir plus ritonavir, pyrazinamide, rifampicin, ritonavir, virus DNA, zidovudine, acute respiratory tract disease, add on therapy, antibiotic sensitivity, antibiotic therapy, article, case report, catch up growth, CD4 lymphocyte count, female, highly active antiretroviral therapy, human, Human immunodeficiency virus infection, immune reconstitution inflammatory syndrome, infant, lung cavitation, lung tuberculosis, lymphadenopathy, Mycobacterium tuberculosis, patient compliance, polymerase chain reaction, prenatal care, thorax radiography, treatment duration, treatment response, vertical transmission, virus load
Citation
Southern African Journal of HIV Medicine
33