The role of bile acids in nutritional support

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dc.contributor.authorVan Niekerk, Gustaven_ZA
dc.contributor.authorDavis, Tanja Andreaen_ZA
dc.contributor.authorDe Villiers, Willemen_ZA
dc.contributor.authorEngelbrecht, Anna-Marten_ZA
dc.date.accessioned2018-10-01T05:40:27Z
dc.date.available2018-10-01T05:40:27Z
dc.date.issued2018-09-30
dc.date.updated2018-09-30T03:55:21Z
dc.descriptionCITATION: Van Niekerk, G. et al. 2018. The role of bile acids in nutritional support. Critical Care, 22:231, doi:10.1186/s13054-018-2160-4.
dc.descriptionThe original publication is available at https://ccforum.biomedcentral.com
dc.description.abstractAbstract: Nutritional support continues to receive much attention as a possible intervention to prevent loss of lean tissue mass, promote recovery and re-establish proper immune function in critical care patients. Yet there remains much controversy regarding the clinical efficacy of such interventions. In addition to the direct effect of nutrition in terms of micro- and macronutrient content, nutritional formulations may exert an effect via the physiological response to feeding. Here, we highlight the key role of postprandial reabsorbed bile acids in attenuating both the inflammatory response and autophagy. These observations suggest that not all patients would benefit from aggressive nutritional support.
dc.description.sponsorshipCancer Association of South Africa
dc.description.sponsorshipNational Research Foundation
dc.description.sponsorshipSouth African Medical Research Council
dc.description.urihttps://ccforum.biomedcentral.com/articles/10.1186/s13054-018-2160-4
dc.description.versionPublisher's version
dc.format.extent6 pages
dc.identifier.citationVan Niekerk, G. et al. 2018. The role of bile acids in nutritional support. Critical Care, 22:231, doi:10.1186/s13054-018-2160-4.
dc.identifier.issn1364-8535 (online)
dc.identifier.otherdoi:10.1186/s13054-018-2160-4.
dc.identifier.urihttp://hdl.handle.net/10019.1/104541
dc.language.isoen
dc.publisherBioMed Central
dc.rights.holderAuthors retain copyright
dc.subjectBile ductsen_ZA
dc.subjectNutritionen_ZA
dc.subjectCritically ill -- Nutritionen_ZA
dc.titleThe role of bile acids in nutritional supporten_ZA
dc.typeArticle
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