A simple automated system for the routine production of (99m)Tc by methyl ethyl ketone extraction
Klopper, J. F.
Van Heerden, P. D. R.
Muller, U. D.
Baard, W. P.
A relatively simple, automated system for the rapid, efficient and safe routine production of 99Tc(m)O4 from 99Mo03 by the metyl ethyl ketone (MEK) extraction technique is described. The 4 phases of the extraction process (bubbling of air, phase separation, drawing off of 99Tc(m) in MEK, and evaporation to dryness) are controlled by an automatic timer, suction pressure pump and solenoid switches. The eluate was found to contain neither bacterial organisms or pyrogens nor significant levels of alumina and radioisotopic impurities. With this system it is possible to make use of locally produced 99Mo, even of low specific activity for the routine production of 99Tc(m) in any concentration required.
The original publication is available at http://www.samj.org.za
Drug isolation, Methyl-ethyl-ketone extraction technique, Drug contamination
Klopper, J.F., Van Heerden, P. D. R., Muller, U. D. & Baard, W. P. 1974. A simple automated system for the routine production of (99m)Tc by methyl ethyl ketone extraction. South African medical journal, 15 May:995-997.