Prevalence of chronic kidney disease and association with cardiovascular risk factors among teachers in Cape Town, South Africa
Date
2017
Journal Title
Journal ISSN
Volume Title
Publisher
Oxford University Press
Abstract
Background: There is a need to determine the feasibility of conducting studies of chronic diseases among large cohorts of
African patients. One aim of the South African feasibility study was to determine the prevalence of chronic kidney disease
(CKD) and its association with cardiovascular disease (CVD) risk factors among school teachers.
Methods: In a cross-sectional survey of 489 teachers we captured data on demographics, CVD risk factors, anthropometry
and blood pressure. Serum glucose, creatinine, cholesterol and urine protein/creatinine ratio was measured. Glomerular filtration
rate was estimated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) and the Modification of
Diet in Renal Disease study equations.
Results: The mean (± standard deviation) age of the participants was 46.3±8.5 years, with 70.3% being female and 74.6% of
mixed ethnicity. The crude prevalence of CKD using the CKD-EPI equation was 6.1% while the age-adjusted prevalence was
6.4% (95% confidence interval 3.2–9.7%). CKD was associated with the presence of diabetes and higher diastolic blood
pressures.
Conclusions: In our study population of relatively young, working individuals CKD was common, clinically silent and associated
with cardiovascular risk factors. The long-term complications of CKD are serious and expensive to manage and this,
therefore, constitutes an important public health problemfor South Africa.
Description
CITATION: Adeniyi, A. B., et al. 2017. Prevalence of chronic kidney disease and association with cardiovascular risk factors among teachers in Cape Town, South Africa. Clinical Kidney Journal, 10(3):363-369,doi:10.1093/ckj/sfw138.
The original publication is available at https://academic.oup.com/ckj
The original publication is available at https://academic.oup.com/ckj
Keywords
Hypertension, Teachers -- Health and hygiene -- South Africa, Chronic diseases -- Surveys, Kidneys -- Diseases, Cardiovascular system -- Diseases, Health risk assessment, Teachers -- Health risk assessment -- South Africa
Citation
Adeniyi, A. B., et al. 2017. Prevalence of chronic kidney disease and association with cardiovascular risk factors among teachers in Cape Town, South Africa. Clinical Kidney Journal, 10(3):363-369,doi:10.1093/ckj/sfw138