Conservation, divergence, and functions of centromeric satellite DNA families in the Bovidae

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dc.contributor.authorEscudeiro, Anaen_ZA
dc.contributor.authorAdega, Filomenaen_ZA
dc.contributor.authorRobinson, Terence J.en_ZA
dc.contributor.authorHeslop-Harrison, John S.en_ZA
dc.contributor.authorChaves, Raquelen_ZA
dc.date.accessioned2021-11-02T13:33:03Z
dc.date.available2021-11-02T13:33:03Z
dc.date.issued2019
dc.descriptionCITATION: Escudeiro, A., et al. 2019. Conservation, divergence, and functions of centromeric satellite DNA families in the Bovidae. Genome Biology and Evolution, 11(4):1152-1165, doi:10.1093/gbe/evz061.
dc.descriptionThe original publication is available at https://academic.oup.com
dc.description.abstractRepetitive satellite DNA (satDNA) sequences are abundant in eukaryote genomes, with a structural and functional role in centromeric function. We analyzed the nucleotide sequence and chromosomal location of the five known cattle (Bos taurus) satDNA families in seven species from the tribe Tragelaphini (Bovinae subfamily). One of the families (SAT1.723) was present at the chromosomes’ centromeres of the Tragelaphini species, as well in two more distantly related bovid species, Ovis aries and Capra hircus. Analysis of the interaction of SAT1.723 with centromeric proteins revealed that this satDNA sequence is involved in the centromeric activity in all the species analyzed and that it is preserved for at least 15–20 Myr across Bovidae species. The satDNA sequence similarity among the analyzed species reflected different stages of homogeneity/heterogeneity, revealing the evolutionary history of each satDNA family. The SAT1.723 monomer-flanking regions showed the presence of transposable elements, explaining the extensive shuffling of this satDNA between different genomic regions.en_ZA
dc.description.urihttps://academic.oup.com/gbe/article/11/4/1152/5393269
dc.description.versionPublisher's version
dc.format.extent14 pages : illustrations (some color)en_ZA
dc.identifier.citationEscudeiro, A., et al. 2019. Conservation, divergence, and functions of centromeric satellite DNA families in the Bovidae. Genome Biology and Evolution, 11(4):1152-1165, doi:10.1093/gbe/evz061
dc.identifier.issn1759-6653 (online)
dc.identifier.otherdoi:10.1093/gbe/evz061
dc.identifier.urihttp://hdl.handle.net/10019.1/123337
dc.language.isoen_ZAen_ZA
dc.publisherOxford University Press
dc.rights.holderAuthors retain copyright
dc.subjectSatellite DNAen_ZA
dc.subjectBovidae -- Geneticsen_ZA
dc.subjectGenomes -- Animal modelsen_ZA
dc.subjectBovinae -- Hybridizationen_ZA
dc.subjectCaprinaeen_ZA
dc.titleConservation, divergence, and functions of centromeric satellite DNA families in the Bovidaeen_ZA
dc.typeArticleen_ZA
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