Leukaemogenesis in Down's syndrome

Simple item page
dc.contributor.authorGericke, G. S.en_ZA
dc.contributor.authorHesseling, P. B.en_ZA
dc.contributor.authorBrink, S.en_ZA
dc.contributor.authorBecker, W. B.
dc.date.accessioned2011-03-18T14:57:53Z
dc.date.available2011-03-18T14:57:53Z
dc.date.issued1977
dc.descriptionCITATION: Gericke, G. S., et al. 1977. Leukaemogenesis in Down's syndrome. South African Medical Journal, 51(6):158-162.
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractDue to the fixed karotype and documented malignancy risk in patients with Down's syndrome, recently described aetiological factors can be assigned to their proper places in a conceptual framework for leukaemogenesis in these individuals. This is a more profitable approach than those in which various types of karyotypic patterns are matched to different malignancies. It seems that viruses may play a special role, but they need interaction with other factors, most of which are present in Down's syndrome. A unifying concept which may be helpful in establishing research priorities is presented.
dc.description.versionPublisher’s version
dc.identifier.citationGericke, G. S., et al. 1977. Leukaemogenesis in Down's syndrome. South African Medical Journal, 51(6):158-162
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.urihttp://hdl.handle.net/10019.1/7717
dc.language.isoenen_ZA
dc.publisherHealth & Medical Publishing Group
dc.rights.holderSouth African Medical Journal
dc.subjectLeukemia
dc.subjectDown syndrome
dc.titleLeukaemogenesis in Down's syndromeen_ZA
dc.typeArticle
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
gericke_leukemogenesis_1977.pdf
Size:
2.89 MB
Format:
Adobe Portable Document Format
Description:
Download article
Download
Collections
Research Articles (Paediatrics and Child Health)