Regulatory T-cells and high levels of FOXP3 mRNA leads to decreased immune responses in HIV-TB co-infection
dc.contributor.author | Loxton, A. | |
dc.contributor.author | Roberts, T. | |
dc.contributor.author | Black, G. | |
dc.contributor.author | Walzl, G. | |
dc.contributor.author | Ross, Anna Laura (ed) | |
dc.date.accessioned | 2014-05-29T10:10:52Z | |
dc.date.available | 2014-05-29T10:10:52Z | |
dc.date.issued | 2009-10 | |
dc.date.updated | 2013-11-23T08:12:20Z | |
dc.description | Poster presented at the AIDS Vaccine 2009 Conference, Paris, France 19-22 October 2009 | en_ZA |
dc.description | Please cite as follows: | en_ZA |
dc.description | Loxton, A., Roberts, T., Black, G. & Walzl, G. 2009. Regulatory T-cells and high levels of FOXP3 mRNA leads to decreased immune responses in HIV-TB co-infection. Retrovirology, 6(Suppl 3):P230, doi:10.1186/1742-4690-6-S3-P230. | en_ZA |
dc.description | The original publication is available at http://www.retrovirology.com/content/6/S3/P230 | en_ZA |
dc.description.abstract | Background Tuberculosis causes 2 million deaths per year and is the most important opportunistic infection in patients infected with HIV. During the co-infection of HIV/TB, natural regulatory T cells (CD4+ FOXP3+) down regulate Th1/Th2 responses. Our study analysed the regulatory Tcell phenotypes amongst participants dually infected with HIV/TB, HIV or TB alone and healthy HIV negative controls and used it as the basis for analysing anti-TB responses and gene expression in HIV infected participants. | en_ZA |
dc.description.version | Publishers' Version | en_ZA |
dc.identifier.citation | Loxton, A., Roberts, T., Black, G. & Walzl, G. 2009. Regulatory T-cells and high levels of FOXP3 mRNA leads to decreased immune responses in HIV-TB co-infection. Retrovirology, 6(Suppl 3):P230, doi:10.1186/1742-4690-6-S3-P230. | en_ZA |
dc.identifier.issn | 1742-4690 (online) | |
dc.identifier.other | doi:10.1186/1742-4690-6-S3-P230 | |
dc.identifier.uri | http://hdl.handle.net/10019.1/86856 | |
dc.language.iso | en_ZA | en_ZA |
dc.language.rfc3066 | en | en_ZA |
dc.publisher | BioMed Central | en_ZA |
dc.rights.holder | A Loxton et al.; licensee BioMed Central Ltd. | en_ZA |
dc.subject | Tuberculosis -- Immunological aspects | en_ZA |
dc.subject | HIV infections -- Immunological aspects | en_ZA |
dc.subject | T-cell phenotypes | en_ZA |
dc.subject | HIV/TB infections -- Treatment | en_ZA |
dc.subject | Immunologic diseases | en_ZA |
dc.subject | ||
dc.title | Regulatory T-cells and high levels of FOXP3 mRNA leads to decreased immune responses in HIV-TB co-infection | en_ZA |
dc.title.alternative | P16-01. Regulatory T-cells and high levels of FOXP3 mRNA leads to decreased immune responses in HIV-TB co-infection | en_ZA |
dc.type | Presentation | en_ZA |
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