Conventional cerebrospinal fluid investigations in the diagnosis of meningitis

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dc.contributor.authorDonald P.R.
dc.contributor.authorBurger P.J.
dc.contributor.authorBecker W.B.
dc.date.accessioned2011-05-15T16:17:14Z
dc.date.available2011-05-15T16:17:14Z
dc.date.issued1987
dc.description.abstractA 3-year prospective study is reported of the value of conventional cerebrospinal fluid (CSF) investigations in the diagnosis of meningitis. Of 739 cases of aseptic meningitis 74 (10 per cent) had a total CSF cell count >500 × 106/l, a + or more of turbidity present on Pandy's test, a CSF total protein >0.8G1, or a CSF glucose <2.2mmol/l and would have been inappropriately treated for bacterial meningitis using these criteria alone as would 18 (17 per cent) of 108 confirmed viral meningitis cases. Conversely, 10 (7 per cent) of 140 N. meningitidis cases, 3 (6 per cent) of 47 H. influenzae cases, and none of 34 S. pneumoniae cases had a total CSF cell count <500 × 106/l, globulin absent or a trace on Pandy's test, a CSF total protein <0.8 G/l, a CSF glucose >2.2 mmol/l and no organisms visible on microscopy. In a tuberculosis meningitis group of 62 children, 55 (89 per cent) had either a + or more of turbidity on Pandy's test, a CSF protein >0.8 G/l, a CSF glucose < 2.2 mmol/l or acid fast bacilli visible on microscopy. Pandy's test is a simple, but valuable aid to the selection of cases requiring the institution of antibiotic therapy. © 1987 Oxford University Press.
dc.description.versionArticle
dc.identifier.citationJournal of Tropical Pediatrics
dc.identifier.citation33
dc.identifier.citation4
dc.identifier.issn01426338
dc.identifier.other10.1093/tropej/33.4.213
dc.identifier.urihttp://hdl.handle.net/10019.1/14128
dc.subjectarticle
dc.subjectaseptic meningitis
dc.subjectcerebrospinal fluid
dc.subjectchild
dc.subjecthuman
dc.subjectmeningitis
dc.subjectprospective study
dc.subjectprotein cerebrospinal fluid level
dc.subjectSouth Africa
dc.subjectvirus meningitis
dc.subjectCerebrospinal Fluid Proteins
dc.subjectChild
dc.subjectHuman
dc.subjectMeningitis
dc.subjectMeningitis, Aseptic
dc.subjectMeningitis, Viral
dc.subjectProspective Studies
dc.subjectSouth Africa
dc.subjectSupport, Non-U.S. Gov't
dc.titleConventional cerebrospinal fluid investigations in the diagnosis of meningitis
dc.typeArticle
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