The frequency of the delta F508 mutation in the cystic fibrosis genes of 71 unrelated South African cystic fibrosis patients

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dc.contributor.authorHerbert, J. S.en_ZA
dc.contributor.authorRetief, A. E.en_ZA
dc.date.accessioned2011-03-18T14:57:16Z
dc.date.available2011-03-18T14:57:16Z
dc.date.issued1992
dc.descriptionCITATION: Herbert, J. S. & Retief, A. E. 1992. The frequency of the delta F508 mutation in the cystic fibrosis genes of 71 unrelated South African cystic fibrosis patients. South African Medical Journal, 82:13 -15.
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractThe common ΔF508 mutation is present in approximately 70% of mutant cystic fibrosis (CF) genes of European and North American populations. The frequency of the ΔF508 mutation has been established for two groups of South African CF subjects. The mutation was found to be present in 82% and 53% of CF genes of white and coloured (i.e. of mixed ancestry) subjects respectively. These findings assist in providing appropriate counselling to individuals who have a family history of CF and in defining laboratory strategies for the establishment of an efficient genetic service for cystic fibrosis.
dc.description.versionPublisher’s version
dc.format.extent3 pages
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.urihttp://hdl.handle.net/10019.1/7299
dc.language.isoen
dc.publisherHealth & Medical Publishing Group
dc.rights.holderSouth African Medical Journal
dc.subjectCystic fibrosisen_ZA
dc.titleThe frequency of the delta F508 mutation in the cystic fibrosis genes of 71 unrelated South African cystic fibrosis patientsen_ZA
dc.typeArticle
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