HIV and childhood tuberculosis: The way forward

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dc.contributor.authorCotton M.F.
dc.contributor.authorSchaaf H.S.
dc.contributor.authorHesseling A.C.
dc.contributor.authorMadhi S.A.
dc.date.accessioned2011-05-15T16:16:47Z
dc.date.available2011-05-15T16:16:47Z
dc.date.issued2004
dc.description.abstractTuberculosis has been a major cause of morbidity and mortality in under-resourced communities. By causing progressive immunodeficiency, the human immunodeficiency virus (HIV) increases susceptibility to tuberculosis in an already vulnerable community. Similarities in clinical presentation and radiological appearance contribute to diagnostic difficulties, as even in the absence of HIV childhood tuberculosis is not easy to diagnose. The majority of studies thus far have been descriptive and often cross-sectional, but have defined the extent of this complex interaction. There is now a need to undertake prospective diagnostic, therapeutic and prevention studies. An emerging concern is how to integrate antiretroviral with anti-tuberculosis treatment and to explore whether lessons learned in tuberculosis can support antiretroviral therapy. Interactions between therapies for both conditions also need careful study.
dc.description.versionConference Paper
dc.identifier.citationInternational Journal of Tuberculosis and Lung Disease
dc.identifier.citation8
dc.identifier.citation5
dc.identifier.issn10273719
dc.identifier.urihttp://hdl.handle.net/10019.1/13935
dc.subjectantiretrovirus agent
dc.subjectBCG vaccine
dc.subjectefavirenz
dc.subjectisoniazid
dc.subjectpyrazinamide
dc.subjectrifampicin
dc.subjectritonavir
dc.subjecttuberculostatic agent
dc.subjectadult respiratory distress syndrome
dc.subjectBCG vaccination
dc.subjectchemoprophylaxis
dc.subjectchild
dc.subjectclinical feature
dc.subjectclinical trial
dc.subjectconference paper
dc.subjectdifferential diagnosis
dc.subjectdirectly observed therapy
dc.subjectdisease association
dc.subjectdisease exacerbation
dc.subjectdisease predisposition
dc.subjectdrug dose regimen
dc.subjectdrug tolerability
dc.subjectfever
dc.subjecthealth care planning
dc.subjecthuman
dc.subjectHuman immunodeficiency virus
dc.subjectHuman immunodeficiency virus infection
dc.subjectinjection site
dc.subjectlymphadenopathy
dc.subjectmalnutrition
dc.subjectmorbidity
dc.subjectmortality
dc.subjectnucleic acid amplification
dc.subjectpatient compliance
dc.subjectpediatrics
dc.subjectpleura effusion
dc.subjectpolymerase chain reaction
dc.subjectpreventive medicine
dc.subjectpriority journal
dc.subjectprospective study
dc.subjectscoring system
dc.subjectside effect
dc.subjectsystemic disease
dc.subjectthorax radiography
dc.subjecttreatment planning
dc.subjecttuberculin test
dc.subjecttuberculoma
dc.subjecttuberculosis
dc.subjectvulnerable population
dc.subjectAIDS-Related Opportunistic Infections
dc.subjectAnti-Retroviral Agents
dc.subjectAntitubercular Agents
dc.subjectBCG Vaccine
dc.subjectChild
dc.subjectHIV Infections
dc.subjectHumans
dc.subjectTuberculosis
dc.titleHIV and childhood tuberculosis: The way forward
dc.typeConference Paper
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