Troponins and acute coronary syndrome

Abstract

Cardiac muscle injury is defined as the disruption of normal cardiac myocyte membrane integrity resulting in the loss of intracellular constituents such as troponin, creatine kinase, and myoglobin into the extracellular space. The mechanism of injury includes trauma, toxins and viral infections, but ischaemia or infarction – due to an imbalance between the supply and demand of oxygen – is the most common cause.