Antibiotic-resistant Serratia marcescens infection in a hospital

Date
1979-04
Authors
Ambrosio, R. E.
Van Wyk, A .J.
De Klerk, H. C.
Journal Title
Journal ISSN
Volume Title
Publisher
HMPG
Abstract
Over a 12-month period, 74 isolates of Serratia marcescens were obtained from various sources at Tygerberg Hospital. The majority of these isolates were from catheterized patients with urinary tract infections, and were non-pigmented and resistant to all antibiotics tested, excepting amikacin and neomycin. All isolates transferred resistance to tobramycin, gentamicin and tetracycline by conjugation to Escherichia coli recipients as separate markers at low frequency. A non-self-transmissible plasmid conferring resistance to kanamycin, ampicillin and gentamicin was mobilized from Serratia species to E. coli, and became fully self-transmissible in subsequent matings.
Description
Article
The original publication is available at http://www.samj.org.za
Keywords
Antibiotic resistance, Drug resistance, Microbial, Escherichia coli, Klebsiella pneumoniae, Urinary tract Infections, Serratia marcescens, Escherichia coli infections, Drug resistance in microorganisms, Nosocomial infections
Citation
Ambrosia, R. E., van Wyk, A. J., de Klerk, H. C. 1979. Antibiotic-resistant Serratia marcescens infection in a hospital. South African Medical Journal, 55: 584-587