The β-adrenoceptor and endocrine abnormalities in juvenile depression
Date
1990
Journal Title
Journal ISSN
Volume Title
Publisher
Health & Medical Publishing Group
Abstract
Neuro-endocrine disturbances were determined in juvenile depressives and possible correlations with biochemical abnormalities investigated. It was established that, as in adult depressives, the young also showed a high incidence of cortisol non-suppression after dexamethasone administration. In addition, a positive correlation observed between lymphocyte β-adrenoceptor maximal number of binding sites and basal cortisol levels stresses the involvement of the noradrenergic neurotransmission system.
Description
CITATION: Carstens, M. E., Taljaard, J. J. F. & Van Zyl, A. M. 1990. The β-adrenoceptor and endocrine abnormalities in juvenile depression. South African Medical Journal, 77:360-363.
The original publication is available at http://www.samj.org.za
The original publication is available at http://www.samj.org.za
Keywords
Depression in adolescence