Control analysis of adrenal Sseroidogenesis

Genade, Tyrone (2004-12)

Thesis (MSc (Biochemistry))--University of Stellenbosch, 2004.


This study describes: 1. Investigation of product inhibition regarding the metabolism of progesterone in ovine adrenal micosomes. 2. The employment of novel cell culture techniques to study the effect of CYP17 and CYP21 concentration on adrenal progesterone metabolism. 3. The formulation of a mathematical model describing the behaviour of the observed results in point 2.

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