Delivery of patients with early onset, severe pre-eclampsia

Hall D.R
Odendaal H.J
Steyn D.W
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Objectives: To compare the effects of induction/labor to delivery before labor in early onset, severe pre-eclampsia. Methods: Five-year prospective case series. Delivery course and neonatal outcome were examined for 335 women with viable singletons. Results: Induction was successful in 45% of attempts. Women exposed to labor had longer (5.5 days, P<0.0001) admissions to delivery periods and were more often delivered for maternal indications (RR=2.87, 95% CI=1.98-4.16). Their babies were born 1.6 weeks older (P<0.0001) and 352 g heavier (P<0.0001) than those delivered before labor. Babies exposed to labor needed intensive care less often (RR=0.4, 95% CI=0.27-0.58), had lower rates of severe hyaline membrane disease (RR=0.26, 95% CI=0.11-0.59) and sepsis (RR=0.56, 95% CI=0.33-0.93), and were discharged earlier (P<0.0001). Conclusions: Exposure to induction/labor in selected patients is not detrimental to neonatal outcome in early, severe pre-eclampsia. Copyright © 2001 International Federation of Gynecology and Obstetrics. All rights reserved.
betamethasone, dihydralazine, magnesium sulfate, methyldopa, nifedipine, oxytocin, prazosin, prostaglandin E2, adolescent, adult, article, birth weight, cesarean section, delivery, disease severity, female, fetus outcome, hospital discharge, human, hyaline membrane disease, hypertension, intensive care, labor, labor induction, major clinical study, preeclampsia, priority journal, sepsis, Adult, Delivery, Obstetric, Female, Humans, Infant, Newborn, Labor, Induced, Pre-Eclampsia, Pregnancy, Pregnancy Outcome, Prospective Studies, Time Factors
International Journal of Gynecology and Obstetrics