Excretion of technetium 99m hexakismethoxyisobutylisonitrile in milk
Date
1991
Authors
Rubow S.M.
Ellmann A.
Le Roux J.
Klopper J.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
The amount of radioactivity excreted in breast milk following the administration of technetium 99m hexakismethoxyisobutylisonitrile (99mTc-MIBI) to a patient referred for cold spot myocardial scintigraphy was determined. During the first 24 h after administration, only 41.2 kBq 99mTc (0.0084% of the injected dose) was excreted in 448 ml milk with the highest concentration of 0.49 kBq/ml in the first sample. The images obtained show a high concentration of 99mTc-MIBI in the lactating breasts contrary to the very small percentage excreted in the milk. Comparison with various recommendations regarding nursing after administration of radiopharmaceuticals seems to indicate that the administration of 99mTc-MIBI does not necessitate an interruption of breast-feeding.
Description
Keywords
methoxy isobutyl isonitrile technetium tc 99m, adult, article, breast feeding, breast milk, case report, female, heart scintiscanning, human, intravenous drug administration, Adult, Breast Feeding, Case Report, Female, Human, Milk, Human, Myocardial Infarction, Nitriles, Organotechnetium Compounds, Puerperal Disorders, Support, Non-U.S. Gov't, Technetium Tc 99m Sestamibi
Citation
European Journal of Nuclear Medicine
18
5
18
5