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Usefulness of sperm penetration assay in fertility predictions

dc.contributor.authorCoetzee K.
dc.contributor.authorKruger T.F.
dc.contributor.authorMenkveld R.
dc.contributor.authorSwanson R.J.
dc.contributor.authorLombard C.J.
dc.contributor.authorAcosta A.A.
dc.date.accessioned2011-05-15T16:15:35Z
dc.date.available2011-05-15T16:15:35Z
dc.date.issued1989
dc.identifier.citationArchives of Andrology
dc.identifier.citation23
dc.identifier.citation3
dc.identifier.issn01485016
dc.identifier.urihttp://hdl.handle.net/10019.1/13405
dc.description.abstractThe competence of the sperm penetration assay (SPA) to predict male fertility, as determined by normal sperm morphology and the fertilizing potential, as shown by human in vitro fertilization (IVF), was investigated. A significant correlation was obtained between normal sperm morphology and the SPA (Φ = 0.623). A weaker correlation was however obtained with human IVF (Φ = 0.397). Notwithstanding this weak association, a positive SPA (> 10%) was highly predictive (95%) of human IVF success. In contrast, a negative SPA (≤ 10%) was associated with a high rate of false-negative (65%). The SPA does however warn that a male factor may be present, as the mean fertilation rate of this group of patients was markedly reduced. The preincubation period for the spermatozoa did not play a major role in the predictive ability of a SPA outcome.
dc.subjectarticle
dc.subjectcell culture
dc.subjectfertility
dc.subjectfertilization in vitro
dc.subjecthuman
dc.subjecthuman cell
dc.subjectmale
dc.subjectmorphology
dc.subjectpriority journal
dc.subjectspermatozoon
dc.subjectFemale
dc.subjectFertility
dc.subjectFertilization in Vitro
dc.subjectHuman
dc.subjectMale
dc.subjectPredictive Value of Tests
dc.subjectSperm-Ovum Interactions
dc.subjectSpermatozoa
dc.subjectTime Factors
dc.titleUsefulness of sperm penetration assay in fertility predictions
dc.typeArticle
dc.description.versionArticle


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