Post-tuberculosis lung health : perspectives from the First International Symposium

Allwood, B. W. ; van der Zalm, M. M. ; Amaral, A. F. S. ; Byrne, A. ; Datta, S. ; Egere, U. ; Evans, C. A. ; Evans, D. ; Gray, D. M. ; Hoddinott, G. ; Ivanova, O. ; Jones, R. ; Makanda, G. ; Marx, F. M. ; Meghji, J. ; Mpagama, S. ; Pasipanodya, J. G. ; Rachow, A. ; Schoeman, I. ; Shaw, J. ; Stek, C. ; van Kampen, S. ; von Delft, D. ; Walker, N. F. ; Wallis, R. S. ; Mortimer, K. (2020-08-01)

CITATION: Allwood, B. W. et al. 2020. Post-tuberculosis lung health: perspectives from the First International Symposium. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 24(8):820–828. doi:10.5588/ijtld.20.0067

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ALTHOUGH CURABLE, TB frequently leaves the individual with chronic physical and psycho-social impairment, but these consequences have been largely neglected. The 1st International Post-Tuberculosis Symposium (Stellenbosch, South Africa) was held to discuss priorities and gaps in addressing this issue. A barrier to progress has been the varied terminology and nomenclature, so the Delphi process was used to achieve consensus on definitions. Lack of sufficient evidence hampered definitive recommendations in most domains, including prevention and treatment of post-TB lung disease (PTLD), but the discussions clarified the research needed. A consensus was reached on a toolkit for future PTLD measurement and on PTLD patterns to be considered. The importance of extra-pulmonary consequences and progressive impairment throughout the life-course was identified, including TB recurrence and increased mortality. Patient advocates emphasised the need to address the psychological and social impacts post TB and called for clinical guidance. More generally, there is an urgent need for increased awareness and research into post-TB complications.

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