Pseudohypokalaemia and pseudohypoxaemia in a patient with acute myeloid leukaemia

Chothia, Mogamat-Yazied ; Davids, Mogamat Razeen (2020)

CITATION: Chothia, M. Y. & Davids, M. R. 2020. Pseudohypokalaemia and pseudohypoxaemia in a patient with acute myeloid leukaemia. African Journal of Nephrology, 23(1):15-18, doi:10.21804/23-1-3855.

The original publication is available at http://www.journals.ac.za/index.php/ajn/

Article

ENGLISH ABSTRACT: Spurious laboratory results are frequently encountered in patients with haematological disorders and lead to unnecessary additional laboratory investigations and inappropriate treatment. An 80-year-old woman, known with acute myeloid leukaemia, was admitted with suspected sepsis. Laboratory tests revealed a leukocyte count of 358 x 109/L, serum potassium concentration of 2.6 mmol/L and partial pressure of arterial oxygen of 5.3 kPa. The patient did not display any clinical or electrocardiographic features of hypokalaemia and there were no signs of respiratory distress. A diagnosis of pseudohypokalaemia and pseudohypoxaemia was made and inappropriate therapeutic interventions were avoided. Pseudohypokalaemia and pseudohypoxaemia should always be a consideration in patients with hyperleukocytosis due to haematological malignancies, especially when there are no clinical features to support these findings. The inappropriate administration of potassium in such cases may cause serious cardiac arrythmias.

Please refer to this item in SUNScholar by using the following persistent URL: http://hdl.handle.net/10019.1/107734
This item appears in the following collections: