Hepatitis B virus infection as a neglected tropical disease

dc.contributor.authorO'Hara, Geraldine A.en_ZA
dc.contributor.authorMcNaughton, Anna L.en_ZA
dc.contributor.authorMaponga, Tongaien_ZA
dc.contributor.authorJooste, Pieteren_ZA
dc.contributor.authorOcama, Ponsianoen_ZA
dc.contributor.authorChileng, Romaen_ZA
dc.contributor.authorMokaya, Jolynneen_ZA
dc.contributor.authorLiyayi, Mitchell I.en_ZA
dc.contributor.authorWachira, Tabithaen_ZA
dc.contributor.authorGikungi, David M.en_ZA
dc.contributor.authorBurbridge, Lelaen_ZA
dc.contributor.authorO'Donnel, Deniseen_ZA
dc.contributor.authorAkiror, Connie S.en_ZA
dc.contributor.authorSloan, Dereken_ZA
dc.contributor.authorTorimiro, Judithen_ZA
dc.contributor.authorYindom, Louis Marieen_ZA
dc.contributor.authorWalton, Roberten_ZA
dc.contributor.authorAndersson, Moniqueen_ZA
dc.contributor.authorMarsh, Kevinen_ZA
dc.contributor.authorNewton, Roberten_ZA
dc.contributor.authorMatthews, Philippa C.en_ZA
dc.identifier.citationO'Hara, G. A., et al. 2017. Hepatitis B virus infection as a neglected tropical disease. PLOS Neglected Tropical Diseases, 11(10): e0005842, doi:10.1371/journal.pntd.0005842
dc.identifier.issn1935-2735 (online)
dc.identifier.issn1935-2727 (print)
dc.descriptionCITATION: O'Hara, G. A., et al. 2017. Hepatitis B virus infection as a neglected tropical disease. PLOS Neglected Tropical Diseases, 11(10): e0005842, doi:10.1371/journal.pntd.0005842.
dc.descriptionThe original publication is available at
dc.description.abstractENGLISH ABSTRACT: The Global Hepatitis Health Sector Strategy is aiming for “elimination of viral hepatitis as a public health threat” by 2030 [1], while enhanced elimination efforts for hepatitis are also promoted under the broader remit of global Sustainable Development Goals (SDGs) [2]. This is an enormous challenge for hepatitis B virus (HBV) given the estimated global burden of 260 million chronic carriers, of whom the majority are unaware of their infection [3] (Fig 1). We here present HBV within the framework for neglected tropical diseases (NTDs) [4] in order to highlight the ways in which HBV meets NTD criteria and to discuss the ways in which the NTD management paradigm could be used to strengthen a unified global approach to HBV elimination [5]. The major burden of morbidity and mortality from HBV is now borne by tropical and subtropical countries [6]. Many African populations epitomize specific vulnerability to HBV [7], so we here focus particular attention on Africa, both through focus on the existing published literature and through presentation of a unique data set of opinion and experience (see S1 Supporting Information). However, the themes we represent are transferable to other low- and middle-income settings and are relevant on the global stage.en_ZA
dc.format.extent9 pages : illustrationsen_ZA
dc.publisherPublic Library of Science
dc.subjectHepatitis Ben_ZA
dc.subjectHepatitis, Viralen_ZA
dc.subjectDiseases, Tropical
dc.subjectHepatitis B vaccineen_ZA
dc.subjectViral vaccinesen_ZA
dc.titleHepatitis B virus infection as a neglected tropical diseaseen_ZA
dc.description.versionPublisher's version
dc.rights.holderAuthors retain copyright

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