Browsing by Author "Vanqa, Nosivuyile"
Now showing 1 - 3 of 3
Results Per Page
Sort Options
- ItemDifferences in health-related quality of life between HIV-positive and HIV-negative people in Zambia and South Africa : a cross-sectional baseline survey of the HPTN 071 (PopART) trial(Elsevier, 2017) Thomas, Ranjeeta; Burger, Ronelle; Harper, Abigail; Kanema, Sarah; Mwenge, Lawrence; Vanqa, Nosivuyile; Bell-Mandla, Nomtha; Smith, Peter C.; Floyd, Sian; Bock, Peter; Ayles, Helen; Beyers, Nulda; Donnell, Deborah; Fidler, Sarah; Hayes, Richard; Hauck, KatharinaBackground: The life expectancy of HIV-positive individuals receiving antiretroviral therapy (ART) is approaching that of HIV-negative people. However, little is known about how these populations compare in terms of health-related quality of life (HRQoL). We aimed to compare HRQoL between HIV-positive and HIV-negative people in Zambia and South Africa. Methods: As part of the HPTN 071 (PopART) study, data from adults aged 18–44 years were gathered between Nov 28, 2013, and March 31, 2015, in large cross-sectional surveys of random samples of the general population in 21 communities in Zambia and South Africa. HRQoL data were collected with a standardised generic measure of health across five domains. We used β-distributed multivariable models to analyse differences in HRQoL scores between HIV-negative and HIV-positive individuals who were unaware of their status; aware, but not in HIV care; in HIV care, but who had not initiated ART; on ART for less than 5 years; and on ART for 5 years or more. We included controls for sociodemographic variables, herpes simplex virus type-2 status, and recreational drug use. Findings: We obtained data for 19 750 respondents in Zambia and 18 941 respondents in South Africa. Laboratoryconfirmed HIV status was available for 19 330 respondents in Zambia and 18 004 respondents in South Africa; 4128 (21%) of these 19 330 respondents in Zambia and 4012 (22%) of 18 004 respondents in South Africa had laboratory-confirmed HIV. We obtained complete HRQoL information for 19 637 respondents in Zambia and 18 429 respondents in South Africa. HRQoL scores did not differ significantly between individuals who had initiated ART more than 5 years previously and HIV-negative individuals, neither in Zambia (change in mean score –0·002, 95% CI –0·01 to 0·001; p=0·219) nor in South Africa (0·000, –0·002 to 0·003; p=0·939). However, scores did differ between HIV-positive individuals who had initiated ART less than 5 years previously and HIV-negative individuals in Zambia (–0·006, 95% CI –0·008 to –0·003; p<0·0001). A large proportion of people with clinically confirmed HIV were unaware of being HIV-positive (1768 [43%] of 4128 people in Zambia and 2026 [50%] of 4012 people in South Africa) and reported good HRQoL, with no significant differences from that of HIV-negative people (change in mean HRQoL score –0·001, 95% CI –0·003 to 0·001, p=0·216; and 0·001, –0·001 to 0·001, p=0·997, respectively). In South Africa, HRQoL scores were lower in HIV-positive individuals who were aware of their status but not enrolled in HIV care (change in mean HRQoL –0·004, 95% CI –0·01 to –0·001; p=0·010) and those in HIV care but not on ART (–0·008, –0·01 to –0·004; p=0·001) than in HIV-negative people, but the magnitudes of difference were small. Interpretation: ART is successful in helping to reduce inequalities in HRQoL between HIV-positive and HIV-negative individuals in this general population sample. These findings highlight the importance of improving awareness of HIV status and expanding ART to prevent losses in HRQoL that occur with untreated HIV progression. The gains in HRQoL after individuals initiate ART could be substantial when scaled up to the population level.
- ItemFactors impacting on adherence to antiretroviral treatment at False Bay Hospital(Stellenbosch : Stellenbosch University, 2013-03) Vanqa, Nosivuyile; Munro, Greg; Stellenbosch University. Faculty of Economic and Management Sciences. Dept. of Industrial Psychology. Africa Centre for HIV/AIDS Management.ENGLISH ABSTRACT: The purpose of this research was to investigate factors impacting on adherence to antiretroviral treatment on people living with HIV and to further explore challenges they come across with adherence. The primary focus of this investigation relates to the following four themes. (i)To evaluate demographic factors such as age, gender and socio-economic factors and the influence they have or contribution to adherence, in correlation with the effects of cultural and health beliefs in this context. (ii) To establish the significance of counselling and review critical challenging issues that needs consideration. (iii) To investigate the nature of reception (negative or ( positive) that patient receives in this local health facility, including the nature of perceived youth friendliness as it may act as a deterrent for confidentiality with regard to referrals. (iv) To determine perceived relationship between health care providers and patients, by patients in terms of support system, referral systems and the prevention of stigma and discrimination. This study comprises of the literature analysis on adherence globally and in the South African context, reviewing the challenges experienced by many South Africans and people living in this country. The study was implemented at a Government’s facility in a health care sector “False Bay Hospital” in the Western Cape, through one focus group and ten semi-structured interviews with patients. The findings of the study reveal that stigma and discrimination is one of the leading causes to poor adherence on antiretroviral treatment including social problems experienced by PLWA. Support and counselling programmes provided at False Bay Hospital were significant but did not necessarily help PLWA in other challenges they came across with. This study also demonstrated the importance of health education and good relationship with patience has a positive effect towards adherence and improves chances of better health.
- ItemHealing, referring, supporting but not interfering : traditional healers experiences of HIV management in five South African communities taking part in the HPTN 071 (PopART) trial(Stellenbosch : Stellenbosch University, 2020-03) Vanqa, Nosivuyile; Reynolds, Lindsey; Stellenbosch University. Faculty of Arts and Social Sciences. Dept. of Sociology & Social Anthropology.ENGLISH ABSTRACT: No abstract