Browsing by Author "Smith, N."
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- ItemAnti-nutritional factors in canola produced in the Western and Southern Cape areas of South Africa(South African Society for Animal Science, 2007) Brand, T. S.; Smith, N.; Hoffman, L. C.ABSTRACT: The development of low erucic acid, low glucosinolate cultivars of canola seed has led to the availability of a feed ingredient with considerable potential to replace soyabean meal in diets for all classes of farm animals. The sinapine and glucosinolate content of various canola cultivars cultivated in two areas of the Western Cape, South Africa were compared. There were no significant differences in sinapine content between the canola produced in the Western and Southern Cape (mean value of 9.95 mg sinapine/g grain). There were cultivar differences, with Varola 54 and Rainbow cultivars having significantly higher sinapine concentrations than Varola 50. There were no significant differences between the aliphatic, indolyl or aromatic glucosinolate content of the canola originating from either the Swartland or the Ruens areas in South Africa (mean value of 17.84 umol total glucosinolates/g grain). There were significant differences in the total glucosinolate content of the various canola cultivars. Varola 44 and Hylite 200TT had the lowest total glucosinolate concentration and Varola 50 had the highest glucosinolate concentration. The results obtained seem to indicate a maximum dietary inclusion level of up to 14% for South African produced canola with an average of 17.83 umol glucosinolates per gram to ensure optimal animal production.
- ItemSSRI use in pregnancy : evaluating the risks and benefits(AOSIS Publishing, 2015) Du Toit, El.; Thomas, E.; Koen, L.; Vythilingum, B.; Grobler, S.; Smith, N.; Niehaus, D.Selective serotonin reuptake inhibitor (SSRI) antidepressants are considered the primary pharmacological treatment for moderate to severe depression during pregnancy. Data regarding the safety of their use during pregnancy remain controversial and conflicting. Decisions regarding the prescription of antidepressant treatment are often fraught with concern around potential harmful medication effects on the pregnancy, fetus and infant. Information on potential risks remains extremely varied and inconsistent across sources. This lack of clarity regarding drug safety brings significant uncertainty not only for treating physicians, but also for women seeking information about depression during pregnancy. This review aims to summarise and evaluate the current evidence base and to aid clinicians in performing a risk/benefit analysis for SSRI use during pregnancy and lactation.
- ItemUse of sweet lupin, canola oilcake and full-fat canola as alternatives to soybean oilcake in diets for broilers(South African Society for Animal Science, 2018-07-02) Brand, T. S.; Smith, N.; Hoffman, L. C.; Jordaan, L.The effect of replacing soybean oilcake meal as a protein source with three levels (6.6%, 13.0% and 20.0%) of sweet lupin (Lupinus angustifolius), canola oilcake and full-fat canola in diets for broiler chickens was examined. A control diet with soybean oilcake as the protein source was supplemented with alternative test diets containing sweet lupin, canola oilcake or full-fat canola as protein source at 100.0%, 67.0% and 33.0% inclusion level. The test diets were fed for six weeks to determine their potential to enhance the nutritive value of these vegetable protein sources. Broiler weights at six weeks old were significantly higher for the control diet than the 20.0% lupin diet. The feed intake of the 20.0% canola oilcake diet at Week 6 was significantly less than that of the control diet, but not less than the 6.6% and 13.2% canola oilcake diets. The feed conversion ratio (FCR) of the control diet was better than the 13.2% and 20.0% canola oilcake diets. The FCR of the broilers fed the 13.2% and 20.0% full-fat canola diets was significantly poorer than the control diet. From this study it is clear that sweet lupin, canola oilcake meal and full-fat canola can be used at low inclusion levels to partially replace soybean oilcake meal as a protein source in broiler diets.