Browsing by Author "Siebert, Igno"

Now showing 1 - 2 of 2
  • Thumbnail Image
    Item
    An evidence-based approach to recurrent pregnancy loss
    (Health & Medical Publishing Group, 2013-07-26) Van Niekerk, Elzaan C.; Siebert, Igno; Kruger, Theunis Frans
    Recurrent pregnancy loss (RPL) can be defined as more than two to three consecutive miscarriages before 24 weeks’ gestation. A literature review was done to provide an evidence-based approach to RPL, identifying the risk factors and causes and also looking at the various special investigations that form part of the work-up and trying to assess which have been proven to be effective or of negative impact, and which of the management options lead to a better outcome. We concluded that the following special investigations should be part of the work-up for all patients with RPL: (i) genetic counselling and karyotyping of the abortus; (ii) anticardiolipin antibodies and lupus anticoagulant testing must be done on two occasions, 6 - 8 weeks apart; (iii) all patients qualify for a pelvic ultrasound scan and hysteroscopy; (iv) syphilis testing must be done routinely; and (v) testing of thyroid function and glucose monitoring/glycosylated haemoglobin (HbA1c) measurement must be done in all patients with a history of thyroid disease or diabetes mellitus, or clinical manifestations thereof. In approximately 50% of couples the cause of RPL remains unexplained, even after evaluation.
  • Thumbnail Image
    Item
    A new approach to tubal re-anastomosis in South Africa
    (Health & Medical Publishing Group, 2011-05) La Grange, Jane; Kruger, Thinus; Van der Merwe, Kobie; Siebert, Igno; Viola, Maria; Matsaseng, Thabo
    Contraception by means of fallopian tube sterilisation is the most common method used worldwide, and it is estimated that on average 138 million women of reproductive age are sterilised globally each year. Several studies have indicated that the incidence of tubal re-anastomosis in previously sterilised women is 1 - 2%.