Browsing by Author "Mugaboa, Pierre"
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- ItemCharacterization and cardiovascular effects of (13S)-9α,13α-epoxylabda-6β(19),15(14)diol dilactone, a diterpenoid isolated from Leonotis leonurus(University of KwaZulu-Natal, 2008) Obikeze, Kene C.; McKenzie, Jean M.; Green, Ivan R.; Mugaboa, PierreA new diterpenoid, (13S)-9α,13α-epoxylabda-6β(19),15(14)diol dilactone (1), was isolated from Leonotis leonurus and the structure determined via NMR analysis. The compound causes significant changes in blood pressure of anaesthetized normotensive rats and exhibits a negative chronotropic effect.