Browsing by Author "Kotze, T. J. van W."

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    Immunoreactive digitalis-like substance in pre-eclampsia
    (Health & Medical Publishing Group, 1986) Odendaal, H. J.; Beyers, A. D.; Van Heyningen, C. F.; Spruyt, L. L.; Kotze, T. J. van W.; Van Jaarsveld, P. P.
    An endogenous digitalis-like substance (DLS) may be involved in the pathogenesis of essential hypertension and pre-eclampsia. The digoxin levels in maternal and cord blood of 504 randomly selected patients were determined. Since none of the patients received digoxin, these levels indicated a cross-reacting substance (immunoreactive DLS). DLS levels were significantly higher in the cord blood of pre-eclamptic patients than in the cord blood of controls. DLS levels in cord blood increased with the severity of pre-eclampsia, and levels were higher in primigravidas than in multigravidas. The structure and biological activity of DLS must be determined before definite conclusions about its role in the pathogenesis of pre-eclampsia can be made.
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    Die invloed van die rookgewoonte op die simptome van die diffuse obstruktiewe pulmonale sindroom
    (Health & Medical Publishing Group, 1981) Wicht, C. L.; Kotze, T. J. van W.
    In a randomized sample of the Bellville population a high prevalence rate for smoking was found in men (71%) and women (38%). Of the smokers, 73% of men and 42% of women started smoking before the age of 21 years. On the whole men were heavier smokers than women. An inverse relationship between social class and smoking was partly shown. A distinct relationship between smoking in men and symptoms of cough, production of sputum and grad 2 dyspnoea was also shown. In women there was a relation to the symptoms of morning cough and sputum production but, in contrast to men, not to the symptoms of chronic cough and sputum production relating to chronic bronchitis. It appears that men are more susceptible to chronic bronchitis than women. A total of 32% men and 30% women had stopped smoking. Various reasons were given for discontinuing or decreasing smoking, a personal decision being of more importance than a doctor's recommendation.