SUNScholar - Browsing by Author "Cronje, H. S."

Browsing by Author "Cronje, H. S."

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Diagnostic hysteroscopy after postmenopausal uterine bleeding
(Health & Medical Publishing Group, 1984) Cronje, H. S.
Hysteroscopy was done immediately before diagnostic fractional curettage in 93 patients with postmenopausal uterine bleeding, as well as in 84 control patients with premenopausal abnormal uterine bleeding. About 13% of patients in both groups were receiving hormonal therapy, while patients with intra-uterine devices were excluded from the study. Bleeding within the uterine cavity obscured the view at hysteroscopy in 3.6% of premenopausal patients, but in none of the postmenopausal patients. Comparison of the final diagnoses in the two groups revealed more endometrial polyps and carcinoma in the postmenopausal patients. However, no tissue for histological examination was obtained at fractional curettage in 28% of the postmenopausal patients, compared with only 4.8% of premenopausal patients (P < 0.0001). Thus the combined use of hysteroscopy and fractional curettage significantly improves diagnostic accuracy in postmenopausal patients.
The effect of surgical glove powder on cleavage of two-cell mouse embryos in an in vitro fertilization programme
(Health & Medical Publishing Group, 1985) Kruger, T. F.; Cronje, H. S.; Stander, F. S. H.; Menkveld, R.; Conradie, E.
The effect of surgical glove powder on the development of early mouse embryos was studied. Embryos from F1 hybrid mice (C57 B1/6 x CBA) were suspended in Whittingham's T6 growth medium with 10% human serum, using Petri dishes (Falcon 3001). Contamination was brought about by a sterile, powdered, surgical glove touching the surface of the growth medium for less than a second in group I, and in group II the same procedure was followed but the glove was rinsed beforehand with sterile, four times distilled water and air-dried. In the control group (group III) no contamination with surgical glove powder occurred. In group I only 9 of 137 embryos (7%) reached the blastocyst stage, in contrast with 110 of 196 (56%) in group II and 258 of 287 (90%) in group III. The differences in results between groups I and III, groups I and II, and groups II and III were found to be statistically significant (P < 0.001) by the chi-square test. It is concluded that surgical gloves are a potent inhibitor of early embryonic growth. In an in vitro fertilization programme including follicle aspiration and embryo transfer, contamination of embryos with these gloves should be avoided at all costs.
Intra-uterine temperature measurements during fetal tachycardia
(Health & Medical Publishing Group, 1977) Cronje, H. S.
Intra-uterine and oral temperatures were recorded in 23 patients with fetal tachycardia during labor, as well as in 22 patients without fetal tachycardia. In the tachycardia group, the mean intra-uterine temperature was 38,83°C, against 37,44°C in the control group. The oral temperatures were 38,05°C and 36,98°C respectively. Furthermore, a high incidence of neonatal infections occurred in the tachycardia group - 11 against 1 in the control group. To distinguish infection from other causes of fetal tachycardia, intra-uterine temperature measurements could be applied as a diagnostic aid.
Management of anterior vaginal prolapse in South Africa : national survey
(Health and Medical Publishing Group (HMPG), 2009-04) Henn, E. W.; Cronje, H. S.; Van Rensburg, J. A.
To the Editor: A national survey was done on the management of anterior vaginal prolapse (AVP) by registered gynaecologists and urologists in South Africa. Of 822 questionnaires posted, 30.2% were returned completed (23.2% from gynaecologists and 7.0% from urologists). The information supplied was anonymous and is probably a true reflection of current practice. Of concern were the 36.3% of respondents who did not use a recognised staging system, a low rate of pre-operative urodynamic investigation by gynaecologists (8.4%) and a high rate of synthetic mesh use by urologists (75.9%), even for primary procedures. This first survey among South African prolapse surgeons provides valuable insight into clinical practice.
Methods of breech delivery at Tygerberg Hospital
(Health & Medical Publishing Group, 1987-02) Mostert, A.; Cronje, H. S.
ENGLISH ABSTRACT: In a retrospective descriptive study, all breech deliveries in Tygerberg Hospital from 1 October 1982 until 30 September 1983 are presented. The aim of the study was to determine the status of the method of breech deliveries in this hospital. There were 358 breech deliveries, all fetuses weighing 500 g or more. Of these, 80% were live born. Caesarean section accounted for 51,5% of the live births. These results correlate well with those reported in other series.
Prevalence of primary papillary peritoneal neoplasia in patients with ovarian carcinoma
(Health and Medical Publishing Group (HMPG), 1985-06) Lindeque, B. G.; Cronje, H. S.; Deale, C. J. C.
Primary papillary peritoneal neoplasia (PPPN) is a recently recognized disease entity. Macroscopically it resembles ovarian carcinoma. On microscopic examination it also superficially resembles serous ovarian adenocarcinoma, but in PPPN the epithelial cells are single-layered and well differentiated with very rare mitoses, and numerous psammoma bodies are found. In a retrospective review of 61 consecutive patients with serous or papillary ovarian adenocarcinoma seen over a 7-year period, 4 patients with PPPN were found (6.5%). One of these patients was in clinical stage I, 2 were in stage II and 1 was in stage III. All had undergone total abdominal hysterectomy and bilateral salpingo-oophorectomy. Two of these patients received additional chemotherapy and 1 radiotherapy. After 3, 3, 8 and 4 years there were no recurrences in these patients, in contrast to a 29.1% 5-year survival rate for the other patients with serous carcinoma. Cytological examination of ascitic fluid specimens performed in 3 of the 4 patients with PPPN demonstrated the presence of highly differentiated serous tufted cells.
'n Prospektiewe analise van tweelingverlossings oor 'n tydperk van 6 maande in die Tygerberg-hospitaal
(Health & Medical Publishing Group, 1986) Marais, J. G.; Cronje, H. S.
All pregnancies involving twins weighing 500 g and more at birth were followed up prospectively over 6 months. There were 53 twins with a mean gestational age of 36.1 weeks. Vertex presentations occurred in 59.4% of the infants and breech presentations in 40%. There were 72 vaginal deliveries (68%) and 34 caesarean sections (32%). Of the vaginal deliveries 31 were normal vertex deliveries (29.2%), 16 forceps deliveries (15.1%), and 20 breech deliveries (23.6%). The mean birth weight was 2 150 g, with a range of 560 - 3 400 g. A total of 14 infants died (13.2%), 8 in utero and 6 in the neonatal period (≤ 7 days). Infants who survived and those who died during the early neonatal period (≤ 7 days) were compared: the mean gestational ages (36.6 and 33.7 weeks) and mean birth weights (2 280.5 and 1 319.0 g) both differed significantly (P < 0.05), but there were no significant differences in fetal presentation and method of delivery. The caesarean section rate could probably have been lower, since some of the indications were rather vague. Neonatal mortality was significantly influenced by gestational age and birth weight and not by fetal presentation and mode of delivery.
A review of 367 triplet pregnancies
(Health & Medical Publishing Group, 1984) Deale, C. J. C.; Cronje, H. S.
Questionnaires were sent to 452 hospitals in the RSA and SWA/Namibia requesting information on triplet pregnancies over a 10-year period. Information on 367 sets of triplets from 150 hospitals was adequate for analysis. The incidence of triplets was 0,04% of all deliveries. As many as 45% of triplets were diagnosed during the first or second stage of labour. These infants had a significantly lower birth weight than those diagnosed at an antenatal clinic (P <0,01). The mean birth weights of babies that died in utero or neonatally (within 7 days) were significantly lower than those in survivors (P <0,0001). Caesarean section was the delivery method for 14% of 1002 infants and perinatal mortality was improved for the second and third babies in comparison with second and third babies delivered vaginally (P <0,003 and P <0,002 respectively). It is concluded that the diagnosis of triplets should be made at the earliest possible stage of pregnancy, and that following adequate antenatal care all triplets should be delivered by caesarean section, except under ideal uncomplicated conditions where vaginal delivery may be feasible.
The role of hexoprenaline in suprapubic amniocentesis during late pregnancy : a pilot study
(Health & Medical Publishing Group, 1984) Cronje, H. S.; Kruger, T. F.; Bradshaw, D.
Suprapubic amniocentesis is often complicated by the fetal head being fixed in the pelvis, oligohydramnios or a hyperirritable myometrium. These factors limit the success rate associated with the procedure. If the myometrium is relaxed with a β2-stimulant, a higher success rate may be achieved. This was investigated in a randomized, prospective, double-blind pilot study using hexoprenaline. When four- or five-fifths of the fetal head was palpable above the pelvis, hexoprenaline (17 amniocenteses) showed no advantage over a placebo (16 amniocenteses). However, when three-fifths or less of the fetal head was palpable above the brim, 4 dry taps were obtained in the control group using a placebo (17 amniocenteses), while none occurred in the study group (19 amniocenteses) (P < 0.05). Elevation of the fetal head was less difficult in the study group, but this difference was not statistically significant. These results suggest that hexoprenaline is not indicated for routine use during amniocentesis. When a dry tap is obtained or when marked difficulty is encountered in lifting the fetal head from the pelvis, 10 μg hexoprenaline administered intravenously 5 minutes before amniocentesis appears to facilitate successful completion of the procedure. However, a larger series is necessary to confirm this observation.
Staging of endometrial cancer by hysteroscopy
(Health & Medical Publishing Group, 1988) Cronje, H. S.; Deale, C. J. C.
Twenty-four consecutive patients with endometrial adenocarcinoma were staged pre-operatively by hysteroscopy and by fractional dilatation and curettage (D & C) to evaluate the accuracy of each method in differentiating between International Federation of Gynaecology and Obstetrics stage I and II cancer. Hysteroscopic staging was correct in 16 patients (69.6%) and incorrect in 7 (30.4%). In 1 additional patient hysteroscopy failed to diagnose the endometrial cancer. D & C staged 16 patients correctly (66.7%) and 8 incorrectly (33.3%). Where the hysteroscopic and D & C stagings correlated, the staging was correct in 16 patients (75%) and incorrect in 4 (25%). Therefore hysteroscopy and D & C are of similar value in the pre-operative staging of endometrial adenocarcinoma and their combined use has a slight advantage.
Die waarde van histeroskopie as ginekologiese ondersoekprosedure
(Health & Medical Publishing Group, 1981) Cronje, H. S.; Street, B.; Van Niekerk, W. A.
There is a worldwide interest in the use of hysteroscopy in the practice of gynaecology. For this reasons a prospective study has been undertaken on 168 randomly selected patients admitted to the gynaecological wards to evaluate its usefulness. Pre- and postmenopausal abnormal uterine bleeding were the main indications for evaluating these patients. The picture obtained by hysteroscopic examination was carefully correlated with the histopathological diagnosis in each case. In only 7% of cases the hysteroscopic diagnosis differed from that obtained by histological examination of the endometrium. In 1,8% of cases a hysteroscopic investigation could not be done because of active intra-uterine bleeding. Hysteroscopy could be performed as successfully under paracervical block as under general anaesthesia. The conclusion reached was that hysteroscopy is a most important adjunct in the investigational armamentarium of a gynaecologist.

Browsing by Author "Cronje, H. S."

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