Browsing by Author "Cooper, R. C."

Now showing 1 - 4 of 4
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    Aetiology of pulmonary dysfunction in total hip replacement operations: The influence of nifedipine on the factors involved
    (Health & Medical Publishing Group, 1987-05) Du Toit, H. J.; Macfarlane, C. M.; Taljaard, J. J. F.; King, J. B.; Cooper, R. C.
    ENGLISH ABSTRACT: Patients undergoing total hip replacement surgery who developed pulmonary dysfunction (PD) demonstrated evidence of a complement activation and increased thromboxane A2 (TXA2) synthesis. In a double-blind study nifedipine (Adalat; Bayer-Miles) was shown to inhibit complement activation and TXA2 synthesis and thus appears to offer protection against PD.
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    Deficiency of the seventh component of complement : a case report
    (Health & Medical Publishing Group, 1991) Cooper, R. C.; Hendricks, M. L.; Daniels, J.; Coetzee, S.; Potter, P. C.
    Deficiency of the 7th component of the complement cascade was diagnosed in a white male with recurrent meningococcal infections. This deficiency has not previously been reported in South Africa.
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    Enzyme-linked immunosorbent assay for the detection of mycobacterial antigens in the cerebrospinal fluid in tuberculous meningitis
    (Health & Medical Publishing Group, 1987) Donald, P. R.; Cooper, R. C.
    Fifty-three cerebrospinal fluid specimens from meningitis patients were investigated by enzyme-linked immunosorbent assay for detection of mycobacterial antigens. After heating at 56° C for 1 hour to eliminate nonspecific interference, all 22 tuberculous meningitis (TBM) specimens had an optical density of greater than 0.05 (sensitivity 100%). Six out of 31 non-TBM cases gave false-positive results (specificity 81%).
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    Serum immunoglobulin and complement values in onyalai : comparison with black, San and white inhabitants of Kavango, SWA/Namibia
    (Health & Medical Publishing Group, 1986-08) Hesseling, P. B.; Cooper, R. C.; Girdle-Brown, B.
    The hypothesis that onyalai results from a polyclonal immune response and that complement activation occurs in its active phase was investigated. Serum immunoglobulins IgA, IgG and IgM and complement fractions C3 and C4 were measured in 21 black onyalai patients and 44 of their close relatives, 37 healthy black schoolchildren, 42 Barakwenga San, 10 Kung San and 18 whites in Kavango. An additional 4 patients with onyalai were investigated after splenectomy. Total complement level, circulating immune complexes and antinuclear antibodies were measured in an additional 6 patients with acute onyalai. The results did not support the hypothesis.