Browsing by Author "Chama, Abdoulkadri"
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- ItemAnalytical modeling of surface-mounted and consequent-pole linear vernier hybrid machines(Institute of Electrical and Electronics Engineers, 2021) Botha, Christoff D.; Kamper, Maarten J.; Wang, Rong-Jie; Chama, AbdoulkadriENGLISH ABSTRACT: This paper presents an analytical method for modeling the no-load air gap ux density of a surface-mounted and a consequent-pole linear Vernier hybrid machine (LVHM). The approach is based on simple magneto-motive force (MMF) and permeance functions to account for the doubly-slotted air gap of the LVHM. These models are used to determine the ux linkage, induced electromotive force (EMF) and average thrust force of each machine. The accuracy of the two analytical models is validated by comparison with 2D nite element method (FEM) solutions. Based on the analytical models, it is found that the working harmonics of both surface-mounted and consequent-pole LVHMs are essentially the same. However, the magnitudes of these working harmonics in the consequent-pole LVHM are invariably greater than those of surface-mounted LVHM. Further, using the analytical model, the contribution to the thrust force of the machine by each individual working harmonic can be shown clearly, and is used to explain why the consequent-pole LVHM has improved performance despite using only 50% of the permanent magnet (PM) material compared to the surface-mounted LVHM.
- ItemFrequency sensitive mechanism in low-intensity ultrasound enhanced bioeffects(Public Library of Science, 2017) Miller, April D.; Chama, Abdoulkadri; Louw, Tobias M.; Subramanian, Anuradha; Viljoen, Hendrik J.This study presents two novel theoretical models to elucidate frequency sensitive nuclear mechanisms in low-intensity ultrasound enhanced bioeffects. In contrast to the typical 1.5 MHz pulsed ultrasound regime, our group previously experimentally confirmed that ultrasound stimulation of anchored chondrocytes at resonant frequency maximized gene expression of load inducible genes which are regulatory markers for cellular response to external stimuli. However, ERK phosphorylation displayed no frequency dependency, suggesting that the biochemical mechanisms involved in enhanced gene expression is downstream of ERK phosphorylation. To elucidate such underlying mechanisms, this study presents a theoretical model of an anchored cell, representing an in vitro chondrocyte, in an ultrasound field. The model results showed that the mechanical energy storage is maximized at the chondrocyte’s resonant frequency and the energy density in the nucleus is almost twice as high as in the cytoplasm. Next, a mechanochemical model was developed to link the mechanical stimulation of ultrasound and the increased mechanical energy density in the nucleus to the downstream targets of the ERK pathway. This study showed for the first time that ultrasound stimulation induces frequency dependent gene expression as a result of altered rates of transcription factors binding to chromatin.