Illuminating the interrelated immune and endocrine adaptations after multiple exposures to short immobilization stress by in vivo blocking of IL-6

Simple item page
dc.contributor.authorSmith, C.
dc.contributor.authorWilson, N. W.
dc.contributor.authorLouw, Ann
dc.contributor.authorMyburgh, K. H.
dc.date.accessioned2012-02-09T14:41:02Z
dc.date.issued2006-12
dc.descriptionThe original publication is available at http://www.ajpregu.orgen_ZA
dc.description.abstractACUTE PSYCHOLOGICAL STRESS is known to activate the hypothalamic- pituitary-adrenal (HPA) axis, resulting in transiently increased release of inflammatory cytokines (28) and glucocorticoids (45). In contrast, multiple exposures to stress lead to adaptive responses in target tissues such as liver, skeletal muscle, and immune cells. These responses may be influenced by the severity of the stressor and the duration of the stress exposure. The endocrine and cytokine responses are known to be interrelated but are complex and still incompletely understood.en_ZA
dc.description.versionPublishers' Versionen_ZA
dc.format.extentp. R1439-R1447 : ill.en_ZA
dc.identifier.citationSmith, C., Wilson, N. W., Louw, A. & Myburgh, K. H. 2006. Illuminating the interrelated immune and endocrine adaptations after multiple exposures to short immobilization stress by in vivo blocking of IL-6. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 292(--),1439-1447, doi:10.1152/ajpregu.00602.2006.en_ZA
dc.identifier.issn1522-1490 (online)
dc.identifier.issn0363-6119 (print)
dc.identifier.otherdoi:10.1152/ajpregu.00602.2006
dc.identifier.urihttp://hdl.handle.net/10019.1/19689
dc.language.isoen_ZAen_ZA
dc.publisherAmerican Physiological Societyen_ZA
dc.rights.holderAmerican Physiological Societyen_ZA
dc.subjectStress (Psychology) -- Testingen_ZA
dc.subjectGlucocorticoid Receptorsen_ZA
dc.subjectHypothalamic-pituitary-adrenal axisen_ZA
dc.subjectPeripheral blood mononuclear cell functionen_ZA
dc.titleIlluminating the interrelated immune and endocrine adaptations after multiple exposures to short immobilization stress by in vivo blocking of IL-6en_ZA
dc.typeArticleen_ZA
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
louw_illuminating_2006.pdf
Size:
247.98 KB
Format:
Adobe Portable Document Format
Description:
Publishers' Version
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.95 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Research Articles (Physiological Sciences)