Treatment of male sperm autoimmunity by using the gamete intrafallopian transfer procedure with washed spermatozoa

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dc.contributor.authorVan der Merwe, Jacobus P.en_ZA
dc.contributor.authorKruger, Thinus F. K.en_ZA
dc.contributor.authorWindt, Marie-Lenaen_ZA
dc.contributor.authorHulme, Victor A.en_ZA
dc.contributor.authorMenkveld Roelofen_ZA
dc.date.accessioned2011-05-15T16:16:28Z
dc.date.available2011-05-15T16:16:28Z
dc.date.issued1990
dc.descriptionCITATION: Van Der Merwe, J. P., et al. 1990. Treatment of male sperm autoimmunity by using the gamete intrafallopian transfer procedure with washed spermatozoa. Fertility and Sterility, 53(4):682–687, doi:10.1016/S0015-0282(16)53464-5.
dc.descriptionThe original publication is available at http://www.fertstert.org
dc.description.abstractSixteen couples were diagnosed as having immunological infertility. To detect sperm-bound immunoglobulin (Ig), i.e., IgA, IgG, and IgM antibodies, the direct immunobead test (IBT) was used. In each individual patient, the direct IBT was ≥70% positive for either IgA of IgG or both. The indirect IBT was positive for IgA and IgG antibodies in the serum of all the patients. Semen was collected in 15 mL medium (Ham's F10 [Gibco, Grand Island, NY] + 10% whole blood serum) and prepared with the wash and swim-up method. Patients in the study group were treated for their immunological infertility problem by performing the gamete intrafallopian transfer (GIFT) procedure. An ongoing pregnancy was achieved in 7 of the 16 (43%) couples treated with the GIFT procedure with an ongoing pregnancy rate of 24.1% (7 of 29) per cycle. The GIFT procedure appears to be an effective and safe way of treating male immunological infertility.
dc.description.urihttp://www.fertstert.org/article/S0015-0282(16)53464-5/abstract
dc.description.versionPost print
dc.format.extent6 pagesen_ZA
dc.identifier.citationVan Der Merwe, J. P., et al. 1990. Treatment of male sperm autoimmunity by using the gamete intrafallopian transfer procedure with washed spermatozoa. Fertility and Sterility, 53(4):682–687, doi:10.1016/S0015-0282(16)53464-5
dc.identifier.issn1556-5653 (online)
dc.identifier.issn0015-0282 (print)
dc.identifier.otherdoi:10.1016/S0015-0282(16)53464-5
dc.identifier.urihttp://hdl.handle.net/10019.1/13793
dc.publisherElsevieren_ZA
dc.publisherElsevieren_ZA
dc.subjectAutoimmunity -- Spermatozoaen_ZA
dc.subjectInfertility, Maleen_ZA
dc.subjectGametesen_ZA
dc.titleTreatment of male sperm autoimmunity by using the gamete intrafallopian transfer procedure with washed spermatozoa
dc.typeArticle
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