Functional classification of chronic airflow limitation based on flow-volume and single-breath nitrogen washout criteria

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dc.contributor.authorBrundler J.P.
dc.contributor.authorLewis C.M.
dc.contributor.authorDe Kock M.A.
dc.date.accessioned2011-05-15T16:17:53Z
dc.date.available2011-05-15T16:17:53Z
dc.date.issued1983
dc.description.abstractA simple means of functional classification of the individual patient has been devised. The performance of a forced flow-volume manoeuvre in concert with a single-breath nitrogen washout procedure in 54 comprehensively investigated patients with chronic airflow limitation yielded two parameters which could be employed in classification. A normalized alveolar nitrogen slope (FEV1/FVC · ΔN2%) greater than 4.0% per litre clearly delineated emphysema. The peak flow ratio (PEFR/PIFR%) categorized other subgroupings: a value in excess of 100% strongly suggests primary bronchial disease, while a lower value almost certainly indicates a mixed functional disorder.
dc.description.versionArticle
dc.identifier.citationRespiration
dc.identifier.citation44
dc.identifier.citation1
dc.identifier.issn00257931
dc.identifier.urihttp://hdl.handle.net/10019.1/14410
dc.subjectairway obstruction
dc.subjectdiagnosis
dc.subjecthuman
dc.subjectlung flow volume curve
dc.subjectmajor clinical study
dc.subjectmethodology
dc.subjectnitrogen washout
dc.subjectrespiratory system
dc.subjectsingle breath nitrogen test
dc.subjectForced Expiratory Flow Rates
dc.subjectHuman
dc.subjectLung Diseases, Obstructive
dc.subjectNitrogen
dc.subjectPulmonary Emphysema
dc.subjectPulmonary Ventilation
dc.titleFunctional classification of chronic airflow limitation based on flow-volume and single-breath nitrogen washout criteria
dc.typeArticle
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