50 years of Emmonsia disease in humans : the dramatic emergence of a cluster of novel fungal pathogens

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dc.contributor.authorSchwartz, Ilan S.en_ZA
dc.contributor.authorKenyon, Chrisen_ZA
dc.contributor.authorFeng, Peiyingen_ZA
dc.contributor.authorGovender, Nelesh P.en_ZA
dc.contributor.authorDukik, Karolinaen_ZA
dc.contributor.authorSigler, Lynneen_ZA
dc.contributor.authorJiang, Yanpingen_ZA
dc.contributor.authorStielow, J. Benjaminen_ZA
dc.contributor.authorMunoz, Jose F.en_ZA
dc.contributor.authorCuomo, Christina A.en_ZA
dc.contributor.authorBotha, Alfreden_ZA
dc.contributor.authorStchigel, Alberto M.en_ZA
dc.contributor.authorDe Hoog, G. Sybrenen_ZA
dc.date.accessioned2016-08-22T07:07:02Z
dc.date.available2016-08-22T07:07:02Z
dc.date.issued2015
dc.descriptionCITATION: Schwartz, I. S. et al. 2015. 50 years of Emmonsia disease in humans : the dramatic emergence of a cluster of novel fungal pathogens. PLoS Pathogens, 11(11): e1005198, doi:10.1371/journal.ppat.1005198.
dc.descriptionThe original publication is available at http://journals.plos.org/plospathogens
dc.description.abstractNew species of Emmonsia-like fungi, with phylogenetic and clinical similarities to Blastomyces and Histoplasma, have emerged as causes of systemic human mycoses worldwide. They differ from classical Emmonsia species by producing a thermally-dependent, yeast-like phase rather than adiaspores, and by causing disseminated infections, predominantly in immunocompromised patients and often with high case-fatality rates. Such differences will be important for clinicians to consider in diagnosis and patient management, and for microbiologists who may encounter these fungi with increasing frequency.en_ZA
dc.description.sponsorshipFonds Wetenschappelijk Onderzoek— Vlaanderen (G051414N)en_ZA
dc.description.sponsorshipAssociation of Medical Microbiologyen_ZA
dc.description.sponsorshipColciencias Doctorate Program, Colciencias grant 1222-56934875en_ZA
dc.description.sponsorshipInfectious Diseases-Astellas postresidency research fellowshipen_ZA
dc.description.sponsorshipMarie Curie International Research Staff Exchange Scheme grant (to ISS)en_ZA
dc.description.sponsorshipUniversidad de Antioquia “Sostenibilidad" 2014/15 (to JFM)en_ZA
dc.description.urihttp://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1005198
dc.description.versionPublisher's version
dc.format.extent8 pages, images
dc.identifier.citationSchwartz, I. S. et al. 2015. 50 years of Emmonsia disease in humans : the dramatic emergence of a cluster of novel fungal pathogens. PLoS Pathogens, 11(11): e1005198, doi:10.1371/journal.ppat.1005198.
dc.identifier.issn1553-7374 (online)
dc.identifier.otherdoi:10.1371/journal.ppat.1005198
dc.identifier.urihttp://hdl.handle.net/10019.1/99426
dc.language.isoen_ZAen_ZA
dc.publisherPublic Library of Science
dc.rights.holderAuthors retain copyright
dc.subjectEmmonsiaen_ZA
dc.subjectFungal diseaseen_ZA
dc.subjectCandidaen_ZA
dc.subjectMycosesen_ZA
dc.title50 years of Emmonsia disease in humans : the dramatic emergence of a cluster of novel fungal pathogensen_ZA
dc.typeArticleen_ZA
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