In vitro evaluation of ampicillin-gentamicin interactions

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dc.contributor.authorVan der Bijl P.
dc.contributor.authorSeifart H.I.
dc.contributor.authorNat R.
dc.date.accessioned2011-05-15T16:02:02Z
dc.date.available2011-05-15T16:02:02Z
dc.date.issued1989
dc.description.abstractAmpicillin at a concentration of 100 μg/mL was combined in vitro with either gentamicin 10 μg/mL in serum, 0.01 mol/L phosphate-buffered saline at 37°C, or water at room temperature (25°C). At these concentrations, which represent the peak prophylactic serum concentrations likely to be achieved by a 70-kg person after parenteral administration of 1.5 mg/kg gentamicin and 2 g of ampicillin, no clinically significant inactivating effects of these antibiotics on each other were observed over a period of six hours.
dc.description.versionArticle
dc.identifier.citationJournal of Oral and Maxillofacial Surgery
dc.identifier.citation47
dc.identifier.citation5
dc.identifier.issn2782391
dc.identifier.urihttp://hdl.handle.net/10019.1/12275
dc.subjectampicillin
dc.subjectgentamicin
dc.subjectdrug mixture
dc.subjecthuman
dc.subjectin vitro study
dc.subjectintravenous drug administration
dc.subjectoral surgery
dc.subjectpriority journal
dc.subjectsurgery
dc.subjectAmpicillin
dc.subjectChromatography, High Pressure Liquid
dc.subjectDrug Interactions
dc.subjectGentamicins
dc.subjectHuman
dc.subjectIn Vitro
dc.subjectTemperature
dc.titleIn vitro evaluation of ampicillin-gentamicin interactions
dc.typeArticle
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