Homocysteine in vascular disease: An emerging clinical perspective

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dc.contributor.authorJacobs P.
dc.contributor.authorWood L.
dc.contributor.authorBick R.
dc.date.accessioned2011-05-15T16:15:53Z
dc.date.available2011-05-15T16:15:53Z
dc.date.issued2006
dc.description.abstractTraditionally, arterial and venous thrombo-embolism has been attributed to pathophysiological lesions in the vessel wall, or altered blood contents or flow through the lumen. Logically these fall into the category of a high-shear system, as opposed to the rather different circumstances in slowly moving columns of blood. The re-evaluation of this belief has been prompted by acknowledgement that there is currently a shift in emphasis. Recently we have recognised a common central factor in the internal dysfunction of the vessel that precedes and so initiates thrombocyte adhesion.
dc.description.versionReview
dc.identifier.citationCardiovascular Journal of South Africa
dc.identifier.citation17
dc.identifier.citation3
dc.identifier.issn10159657
dc.identifier.urihttp://hdl.handle.net/10019.1/13533
dc.subjectfolic acid
dc.subjecthomocysteine
dc.subjectblood vessel wall
dc.subjectclinical practice
dc.subjectclinical trial
dc.subjectcoronary artery blood flow
dc.subjecthuman
dc.subjectpathophysiology
dc.subjectreview
dc.subjectscreening test
dc.subjectthrombocyte adhesion
dc.subjectthromboembolism
dc.subjectunspecified side effect
dc.subjectvascular disease
dc.subjectAnimals
dc.subjectAtherosclerosis
dc.subjectEndothelium, Vascular
dc.subjectGenetic Predisposition to Disease
dc.subjectHomocysteine
dc.subjectHumans
dc.subjectThrombophilia
dc.subjectVascular Diseases
dc.titleHomocysteine in vascular disease: An emerging clinical perspective
dc.typeReview
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