Early pre-eclampsia: What proportion of women qualify for expectant management and if not, why not?

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dc.contributor.authorHall D.R.
dc.contributor.authorGrove D.
dc.contributor.authorCarstens E.
dc.date.accessioned2011-05-15T16:16:21Z
dc.date.available2011-05-15T16:16:21Z
dc.date.issued2006
dc.description.abstractObjective: To determine what proportion of women with early pre-eclampsia qualify for expectant management and the magnitude of factors excluding this approach. Study design: A prospective case series with continuous data capture over one year at a tertiary referral centre. All women (n = 169) with singleton pregnancies, presenting with early (≥20 and <34 weeks' gestation) pre-eclampsia, were admitted, stabilised and evaluated. Major maternal or fetal complications at this stage were indications for delivery. However, when the pregnancy was otherwise stable, expectant management was commenced if the gestation was ≥24 weeks. Termination was offered from 20 to 23 weeks' gestation. Results: Of the 169 women admitted, 82 (48.5%) were managed expectantly and 87 (51.5%) delivered after stabilisation and evaluation. Early fetal distress (32%) and major maternal complications (28%) were the most frequent reasons preventing expectant management. Ascites (18%) and HELLP syndrome (13%) ranked highest amongst the maternal complications. Conclusions: In this study, almost half of the women presenting with early onset pre-eclampsia qualified for expectant management. Early fetal distress was the most frequent reason preventing expectant management. © 2006 Elsevier Ireland Ltd. All rights reserved.
dc.description.versionArticle
dc.identifier.citationEuropean Journal of Obstetrics Gynecology and Reproductive Biology
dc.identifier.citation128
dc.identifier.citation1-2
dc.identifier.issn03012115
dc.identifier.other10.1016/j.ejogrb.2006.01.003
dc.identifier.urihttp://hdl.handle.net/10019.1/13743
dc.subjectantihypertensive agent
dc.subjectbetamethasone
dc.subjectadolescent
dc.subjectadult
dc.subjectarticle
dc.subjectascites
dc.subjectcontrolled study
dc.subjectdelivery
dc.subjectfemale
dc.subjectfetus distress
dc.subjectgestation period
dc.subjectgestational age
dc.subjectHELLP syndrome
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectpreeclampsia
dc.subjectpregnancy
dc.subjectpregnancy complication
dc.subjectpregnancy termination
dc.subjectpriority journal
dc.subjectprospective study
dc.subjecttreatment indication
dc.subjectAdolescent
dc.subjectAdult
dc.subjectFemale
dc.subjectFetal Distress
dc.subjectHumans
dc.subjectPatient Care Management
dc.subjectPre-Eclampsia
dc.subjectPregnancy
dc.subjectPregnancy Outcome
dc.subjectPrenatal Care
dc.subjectProspective Studies
dc.subjectSouth Africa
dc.titleEarly pre-eclampsia: What proportion of women qualify for expectant management and if not, why not?
dc.typeArticle
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