Urinary protein excretion and expectant management of early onset, severe pre-eclampsia

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dc.contributor.authorHall D.R.
dc.contributor.authorOdendaal H.J.
dc.contributor.authorSteyn D.W.
dc.contributor.authorGrove D.
dc.date.accessioned2011-05-15T16:16:42Z
dc.date.available2011-05-15T16:16:42Z
dc.date.issued2002
dc.description.abstractObjective: To evaluate the importance of proteinuria in the expectant management of early onset, severe pre-eclampsia. Methods: In this prospective series of 340 women, 24-h urine collections were performed and monitored twice weekly in a high-care ward. Results: Seventy-four women with at least two 24-h urine collections were grouped into women with a proteinuria increase of ≥2 g (n=29) and with women whose proteinuria decreased, or increased by <2 g (n=45). Major maternal complications, prolongation of gestation, and perinatal outcomes were comparable. Fifty-six (75%) women experienced an increase in proteinuria. When patients with heavy proteinuria (n=83) were compared to those with moderate proteinuria (n=257), maternal and perinatal outcomes were comparable. More days were gained before delivery in the heavy proteinuria group than in the moderate (12 vs. 9; P<0.001). Conclusion: Most patients experienced increased proteinuria. Neither the rate of increase nor the amount of proteinuria affected maternal and perinatal outcomes. Copyright © 2002 International Federation of Gynecology and Obstetrics.
dc.description.versionArticle
dc.identifier.citationInternational Journal of Gynecology and Obstetrics
dc.identifier.citation77
dc.identifier.citation1
dc.identifier.issn00207292
dc.identifier.other10.1016/S0020-7292(02)00008-5
dc.identifier.urihttp://hdl.handle.net/10019.1/13897
dc.subjectadult
dc.subjectarticle
dc.subjectcontrolled study
dc.subjectdisease course
dc.subjectdisease severity
dc.subjectfemale
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectmaternal morbidity
dc.subjectperinatal development
dc.subjectperinatal period
dc.subjectpreeclampsia
dc.subjectpregnancy
dc.subjectpriority journal
dc.subjectprospective study
dc.subjectprotein urine level
dc.subjectproteinuria
dc.subjectAbruptio Placentae
dc.subjectAdolescent
dc.subjectAdult
dc.subjectFemale
dc.subjectGestational Age
dc.subjectHumans
dc.subjectPre-Eclampsia
dc.subjectPregnancy
dc.subjectPregnancy Outcome
dc.subjectProspective Studies
dc.subjectProteinuria
dc.titleUrinary protein excretion and expectant management of early onset, severe pre-eclampsia
dc.typeArticle
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