Regional distribution of monoamines in the nucleus accumbens of the rat

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dc.contributor.authorAllin R.
dc.contributor.authorRussell V.A.
dc.contributor.authorLamm M.C.L.
dc.contributor.authorTaljaard J.J.F.
dc.date.accessioned2011-05-15T16:17:28Z
dc.date.available2011-05-15T16:17:28Z
dc.date.issued1988
dc.description.abstractMonoamine concentrations were low in the rostral area of the nucleus accumbens. Their distributions were not identical. Differences were observed in the medial area. DA concentrations were high in both medial and caudal areas. Noradrenaline (NA) and serotonin (5-HT) concentrations were considerably lower than the dopamine (DA) concentration. The NA concentration was highest in the caudal area of the nucleus accumbens and the (5-HT) concentration was highest in the ventrocaudal area. There was a rostrocaudal decrease in the 3,4-dihydroxyphenylacetic acid (DOPA)/DA and 5-hydroxyindole-3-acetic acid (5-HIAA)/5-HT ratios. Uptake of [3H]DA and [14C]choline was lowest in the rostral area. The K+-stimulated release of [14C]acetylcholine (ACh) was also lowest rostrally, but there was no rostrocaudal difference in the K+-stimulated release of [3H]DA. These results provide further evidence of the heterogeneity of the nucleus accumbens.
dc.description.versionArticle
dc.identifier.citationNeurochemical Research
dc.identifier.citation13
dc.identifier.citation10
dc.identifier.issn03643190
dc.identifier.urihttp://hdl.handle.net/10019.1/14232
dc.subjectacetylcholine
dc.subjectdopamine
dc.subjectneurotransmitter
dc.subjectnoradrenalin
dc.subjectradioisotope
dc.subjectserotonin
dc.subjectanimal cell
dc.subjectmale
dc.subjectnonhuman
dc.subjectnucleus accumbens
dc.subjectpriority journal
dc.subjectrat
dc.subjectAnimal
dc.subjectBiogenic Monoamines
dc.subjectDopamine
dc.subjectIn Vitro
dc.subjectMale
dc.subjectNorepinephrine
dc.subjectNucleus Accumbens
dc.subjectRats
dc.subjectRats, Inbred Strains
dc.subjectSeptal Nuclei
dc.subjectSerotonin
dc.subjectSupport, Non-U.S. Gov't
dc.titleRegional distribution of monoamines in the nucleus accumbens of the rat
dc.typeArticle
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