Treatment of male urethral strictures: Is repeated dilation or internal urethrotomy useful?

Simple item page
dc.contributor.authorHeyns C.F.
dc.contributor.authorSteenkamp J.W.
dc.contributor.authorDe Kock M.L.S.
dc.contributor.authorWhitaker P.
dc.date.accessioned2011-05-15T16:17:14Z
dc.date.available2011-05-15T16:17:14Z
dc.date.issued1998
dc.description.abstractPurpose: We evaluate the efficacy of repeated dilation or urethrotomy as treatment of male urethral strictures. Materials and Methods: Between January 1991 and January 1994, 210 men with proved urethral strictures were prospectively randomized to undergo filiform dilation (106) or internal urethrotomy (104). Followup was scheduled at 3, 6, 9, 12, 24, 36 and 48 months. Dilation or internal urethrotomy was repeated at the first and second stricture recurrence. The Kaplan-Meier method was used to estimate survivor function for the treatment methods (survival time being the time to first stricture recurrence) and the log rank test was used to compare the efficacy of different treatments. Results: Followup (mean 24 months, range 2 to 63) was available in 163 patients (78%). After a single dilation or urethrotomy not followed by re-stricturing at 3 months, the estimated stricture-free rate was 55 to 60% at 24 months and 50 to 60% at 48 months. After a second dilation or urethrotomy for stricture recurrence at 3 months the stricture-free rate was 30 to 50% at 24 months and 0 to 40% at 48 months. After a third dilation or urethrotomy for stricture recurrence at 3 and 6 months the stricture-free rate at 24 months was 0 (p<0.0001). Conclusions: Dilation and internal urethrotomy are useful in a select group (approximately 70% of all patients) who are stricture-free at 3 months, and of whom 50 to 60% will remain stricture-free up to 48 months. A second dilation or urethrotomy for early stricture recurrence (at 3 months) is of limited value in the short term (24 months) but of no value in the long term (48 months), whereas a third repeated dilation or urethrotomy is of no value.
dc.description.versionArticle
dc.identifier.citationJournal of Urology
dc.identifier.citation160
dc.identifier.citation2
dc.identifier.issn00225347
dc.identifier.other10.1016/S0022-5347(01)62894-5
dc.identifier.urihttp://hdl.handle.net/10019.1/14131
dc.subjectarticle
dc.subjecthuman
dc.subjectintermethod comparison
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectpriority journal
dc.subjectrecurrence risk
dc.subjectrecurrent disease
dc.subjecttreatment outcome
dc.subjecturethra stricture
dc.subjecturethrotomy
dc.subjectBalloon Dilatation
dc.subjectCohort Studies
dc.subjectCystoscopes
dc.subjectDisease-Free Survival
dc.subjectFluoroscopy
dc.subjectFollow-Up Studies
dc.subjectHumans
dc.subjectLinear Models
dc.subjectMale
dc.subjectProspective Studies
dc.subjectRecurrence
dc.subjectReoperation
dc.subjectRetreatment
dc.subjectUreter
dc.subjectUrethral Stricture
dc.subjectUrinary Catheterization
dc.titleTreatment of male urethral strictures: Is repeated dilation or internal urethrotomy useful?
dc.typeArticle
Files
Collections
Stellenbosch University - Scopus Tygerberg Hospital Publications