An evaluation of dextranomer as a cleansing agent in the treatment of the postphlebitic stasis ulcer

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dc.contributor.authorGroenewald J.H.
dc.date.accessioned2011-03-18T14:57:48Z
dc.date.available2011-03-18T14:57:48Z
dc.date.issued1980
dc.descriptionArticle
dc.description.abstractRecent reports in the literature have indicated that dextranomer (Debrisan; Adcock-Ingram) is an effective cleansing agent for the secreting wound. To evaluate its possible use in the initial cleansing of the infected secreting stasis ulcer, 100 patients were incorporated in a single-blind randomized trial. The mean cleansing time for the Debrisan-treated ulcers was 5.9 days, compared with 15.4 days for the control group receiving standard treatment. The average healing time for ulcers treated with Debrisan and left to heal spontaneously was 4.4 weeks compared with 5.32 weeks for the controls. Debrisan, furthermore, decreased the amount of local tissue edema and alleviated local pain in the majority of patients. It is feasible to use Debrisan for outpatient treatment and without additional staff in a busy clinic. The cost of Debrisan therapy appeared to be reasonable. A hydrophilic cleansing agent such as Debrisan has a definite place in the early treatment of the secreting infected postphlebitic stasis ulcer.
dc.identifier.urihttp://hdl.handle.net/10019.1/7661
dc.subjectdextranomer
dc.subjectcleaning
dc.subjectclinical trial
dc.subjectcontrolled study
dc.subjectdrug therapy
dc.subjecthuman
dc.subjectleg ulcer
dc.subjectperipheral vascular system
dc.subjectphlebitis
dc.subjectpolydextran
dc.subjectrandomized controlled trial
dc.subjecttherapy
dc.subjecttopical drug administration
dc.subjectwound care
dc.subjectChlorohydrins
dc.subjectClinical Trials
dc.subjectComparative Study
dc.subjectDebridement
dc.subjectDextrans
dc.subjectEdema
dc.subjectEpichlorohydrin
dc.subjectFemale
dc.subjectGranulation Tissue
dc.subjectHuman
dc.subjectMale
dc.subjectPain
dc.subjectPhlebitis
dc.subjectPovidone-Iodine
dc.subjectRandom Allocation
dc.subjectTime Factors
dc.subjectVaricose Ulcer
dc.subjectWound Healing
dc.titleAn evaluation of dextranomer as a cleansing agent in the treatment of the postphlebitic stasis ulcer
dc.typeArticle
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