Proportion of tuberculosis transmission that takes place in households in a high-incidence area

Simple item page
dc.contributor.authorVerver S.
dc.contributor.authorWarren R.M.
dc.contributor.authorMunch Z.
dc.contributor.authorRichardson M.
dc.contributor.authorVan Der Spuy G.D.
dc.contributor.authorBorgdorff M.W.
dc.contributor.authorBehr M.A.
dc.contributor.authorBeyers N.
dc.contributor.authorVan Helden P.D.
dc.date.accessioned2011-05-15T15:57:03Z
dc.date.available2011-05-15T15:57:03Z
dc.date.issued2004
dc.description.abstractThe prevalence of infection among household contacts of people with tuberculosis is high. This information frequently guides active case finding. We analysed DNA fingerprints of Mycobacterium tuberculosis from 765 tuberculosis patients in Ravensmead and Uitsig, adjacent suburbs of Cape Town, South Africa. In 129 households in which DNA fingerprints were available for more than one patient, we identified 313 patients, of whom 145 (46%) had a fingerprint pattern matching that of another member of the household. The proportion of transmission in the community that took place in the household was 19%, and therefore, in this high-incidence area, tuberculosis transmission occurs mainly outside the household.
dc.description.versionArticle
dc.identifier.citationLancet
dc.identifier.citation363
dc.identifier.citation9404
dc.identifier.issn1406736
dc.identifier.other10.1016/S0140-6736(03)15332-9
dc.identifier.urihttp://hdl.handle.net/10019.1/10187
dc.subjectarticle
dc.subjectcommunity
dc.subjectdisease transmission
dc.subjecthousehold
dc.subjecthuman
dc.subjectincidence
dc.subjectmedical information
dc.subjectMycobacterium tuberculosis
dc.subjectpriority journal
dc.subjectSouth Africa
dc.subjecttuberculosis
dc.subjectAdult
dc.subjectCluster Analysis
dc.subjectDisease Transmission, Horizontal
dc.subjectDNA Fingerprinting
dc.subjectFamily Characteristics
dc.subjectFemale
dc.subjectHumans
dc.subjectIncidence
dc.subjectMale
dc.subjectMycobacterium tuberculosis
dc.subjectPolymorphism, Restriction Fragment Length
dc.subjectSouth Africa
dc.subjectTuberculosis
dc.titleProportion of tuberculosis transmission that takes place in households in a high-incidence area
dc.typeArticle
Files
Collections
Stellenbosch University - Scopus Publications